Constitutive expression of p-glycoprotein in normal lung alveolar epithelium and functionality in primary alveolar epithelial cultures

L Campbell, ANG Abulrob, LE Kandalaft… - … of Pharmacology and …, 2003 - ASPET
The multidrug resistant (MDR) transporter P-glycoprotein (P-gp) is constitutively expressed
in normal tissues, where its spatial distribution defines it as an important element reducing …

Caveolae: an alternative membrane transport compartment

M Gumbleton, AG Abulrob, L Campbell - Pharmaceutical research, 2000 - Springer
Caveolae are omega-shaped invaginations of the plasma membrane with a diameter of 50-100
nm. Caveolae invaginations can detach from the plasma membrane to form discrete …

Transport of phosphatidylcholine in MDR3-negative epithelial cell lines via drug-induced MDR1 P-glycoprotein

AG Abulrob, M Gumbleton - Biochemical and biophysical research …, 1999 - Elsevier
Human MDR1 P-glycoprotein (P-gp) is a membrane efflux pump for cytotoxics, whereas
MDR3 P-gp is a phosphatidylcholine transporter. We have examined a role for MDR1 P-gp in …

Identification and biological evaluation of grapefruit oil components as potential novel efflux pump modulators in methicillin-resistant Staphylococcus aureus bacterial …

AN Abulrob, MTE Suller, M Gumbleton, C Simons… - Phytochemistry, 2004 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) and MSSA strains were treated with: (a)
grapefruit oil (GFO) components, isolated by chromatography and characterised by NMR …

The effect of fatty acids and analogues upon intracellular levels of doxorubicin in cells displaying P-glycoprotein mediated multidrug resistance

AN Abulrob, M Mason, R Bryce… - Journal of drug …, 2000 - Taylor & Francis
… the monoclonal anti-human P-gp antibody, MRK- 16 and reverse transcriptasepolymerase
chain reaction (RT-PCR) using genespecific primers as we have previously detailed (Abulrob

Air pollutants, epithelial surfaces, and lung disease

JG Sherman, JL Peake, VJ Wong… - LUNG BIOLOGY IN …, 2005 - api.taylorfrancis.com
The epithelial cells of the respiratory system are composed of numerous types, which vary as
a function of location. Each cell type provides for specific needs required at each site along …

[BOOK][B] Comparison of standard treatments of breast cancer with new experimental treatments targeting caveolin-1

J Stetler - 2013 - search.proquest.com
Breast cancer is a complex disease at both an anatomical and molecular levels. The complexity
of the disease is a source of difficulty in identifying and treating the cancer, since varying …

[BOOK][B] Inflammation following exposure to airborne particles in a brown Norway rat model of allergic airway disease

JG Sherman - 2004 - search.proquest.com
Studies suggest a correlation between increased morbidity in individuals with asthma and
high ambient levels of particulate matter (PM). We established a model of allergic airway …

[CITATION][C] CELLULAR AND MOLECULAR-Constitutive Expression of P-Glycoprotein in Normal Lung Alveolar Epithelium and Functionality in Primary Alveolar …

L Campbell, ANG Abulrob… - Journal of …, 2003 - Baltimore: Williams & Wilkins, 1909-

Testování účinnosti antibiotik a přírodních látek proti bakteriím in vitro

B Učíková - 2020 - otik.uk.zcu.cz
Léčba infekčních onemocnění známými antibiotiky se stává čím dál více problematickou a
globální kvůli rostoucí antibakteriální rezistenci a nedostatku účinných antibiotik. Cílem práce …