[HTML][HTML] Brain amino acid requirements and toxicity: the example of leucine

…, I Nissim, O Horyn, B Luhovyy, A Lazarow… - The Journal of …, 2005 - Elsevier
Glutamic acid is an important excitatory neurotransmitter of the brain. Two key goals of brain
amino acid handling are to maintain a very low intrasynaptic concentration of glutamic acid …

Ketogenic diet, amino acid metabolism, and seizure control

…, Y Daikhin, I Nissim, A Lazarow… - Journal of …, 2001 - Wiley Online Library
The ketogenic diet has been utilized for many years as an adjunctive therapy in the
management of epilepsy, especially in those children for whom antiepileptic drugs have not …

Ketogenic diet, brain glutamate metabolism and seizure control

M Yudkoff, Y Daikhin, I Nissim, A Lazarow… - … leukotrienes and essential …, 2004 - Elsevier
We do not know the mode of action of the ketogenic diet in controlling epilepsy. One possibility
is that the diet alters brain handling of glutamate, the major excitatory neurotransmitter …

Response of brain amino acid metabolism to ketosis

…, Y Daikhin, I Nissim, O Horyn, A Lazarow… - Neurochemistry …, 2005 - Elsevier
Our objective was to study brain amino acid metabolism in response to ketosis. The underlying
hypothesis is that ketosis is associated with a fundamental change of brain amino acid …

Brain amino acid metabolism and ketosis

…, Y Daikhin, I Nissim, A Lazarow… - Journal of …, 2001 - Wiley Online Library
The relationship between ketosis and brain amino acid metabolism was studied in mice that
consumed a ketogenic diet (>90% of calories as lipid). After 3 days on the diet the blood …

Immunoassay of insulin using a two-antibody system.

CR Morgan, A Lazarow - Proceedings of the Society for …, 1962 - journals.sagepub.com
Tracer amounts of I131-insulin are precipitated by specific antibodies. The change in
percent precipitated, as increasing amounts of unlabeled insulin are added, forms the basis …

Effect of alloxan on permeability of pancreatic islet tissue in vitro

…, SJ Cooperstein, A Lazarow - American Journal of …, 1964 - journals.physiology.org
The effect of alloxan on the permeability of toadfish islet slices was studied in vitro at 0 C,
pH 7.0. When islet slices were incubated in d-mannitol-1-C 14 , a compound which does not …

Staining of insulin with aldehyde fuchsin

…, G LESTER, A LAZAROW - … of Histochemistry & …, 1966 - journals.sagepub.com
1al) i (l auiol select lye staiusiuig of t lie grtousules us oleussomist unit ed followimig oixidtot
itu hiy KNIuuO4-IlSU4 (Scott, Stain ‘J’eeh. 27: 267, l52). Abuusdant evioleutce suggest 5 1 …

Immunoassay of pancreatic and plasma insulin following alloxan injection of rats

CR Morgan, A Lazarow - Diabetes, 1965 - Am Diabetes Assoc
Male rats of approximately 200 gm. body weight were injected intravenously with alloxan (40
mg. per kilogram body weight). Blood glucose determinations were carried out at periodic …

[PDF][PDF] Studies on the enzymatic basis for the Janus green B staining reaction

A Lazarow, SJ Cooperstein - Journal of Histochemistry & …, 1953 - journals.sagepub.com
In 1900, Michaelis used Janus green B as a supravital stain (20). He observed that filamentous
structures within the cytoplasm of the cell stained with this dye and he recognized that …