A safe and effective vaccine against COVID-19 is urgently needed in quantities that are
sufficient to immunize large populations. Here we report the preclinical development of two …

T cell responses play an important role in protection against beta-coronavirus infections,
including SARS-CoV-2, where they associate with decreased COVID-19 disease severity and …

This paper introduces and evaluates new models for time series count data. The Autoregressive
Conditional Poisson model (ACP) makes it possible to deal with issues of discreteness, …

ATP-sensitive K + channel opening in inner mitochondrial membranes protects hearts from
ischemia-reperfusion (I/R) injury. Opening of the Big conductance Ca 2+ -sensitive K + …

In order to capture observed asymmetric dependence in international financial returns, we
construct a multivariate regime-switching model of copulas. We model dependence with one …

Background Multiple sclerosis (MS) is often accompanied by optic nerve inflammation. And
some patients experience permanent vision loss. We examined if the grade of optic nerve …

We recently demonstrated a role for altered mitochondrial bioenergetics and reactive oxygen
species (ROS) production in mitochondrial Ca 2+ -sensitive K + (mtK Ca ) channel opening-…

Schwann cells are the myelinating glial cells of the peripheral nervous system and establish
myelin sheaths on large caliber axons in order to accelerate their electrical signal …

Aims and objectives To review interventions and strategies designed to progress UK clinical
academic career pathways in nursing and identify barriers and facilitators to aid wider …

Objective To examine the role of psychosocial risk factors for low birthweight. Design A
prospective study. Setting Obstetric outpatient clinics of the University Hospital Vrije Universiteit, …