We conducted the present study to determine whether the angiotensin II type I receptor (AT1)
gene might be implicated in human essential hypertension by using case-control and …

We reported from our previous multicentre case-control study that the deletion (D)
polymorphism of the gene encoding angiotensin-converting enzyme (ACE) was associated with …

Background Charcot–Marie–Tooth neuropathy has been reported to be associated with
renal diseases, mostly focal segmental glomerulosclerosis (FSGS). However, the common …

Endothelium-derived relaxing factor (EDRF)/nitric oxide (NO) is synthesized from L-Arginine
by the endothelial, constitutive, NO synthase. To facilitate genetic studies, we have cloned …

Several clinical and experimental studies have suggested a significant role of angiotensin II
in the development of alterations of small and large arteries. The present study was …

Chronic renal failure (CRF) is associated with an increased bioavailability of drugs by a poorly
understood mechanism. One hypothesis is a reduction in the elimination of drugs by the …

Calcidiol insufficiency is highly prevalent in chronic kidney disease (CKD), but the reasons
for this are incompletely understood. CKD associates with a decrease in liver cytochrome …

Chronic renal failure (CRF) is associated with a decrease in liver drug metabolism, particularly
mediated by the cytochrome P450. CRF also impedes intestinal drug transporters [mainly …

ABSTRACT. Chronic renal failure (CRF) is associated with a decrease in intestinal drug
metabolism. The mechanisms remain poorly understood, but one hypothesis involves a …

Organ transplantation is associated with an early bone loss that subsequently increases the
risk of osteopenia and bone fractures. It is not known whether bone loss continues in long-…