Serotonin2C receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: A combined dialysis and …
…, A Newman‐Tancredi, A Adhumeau‐Auclair… - Synapse, 2000 - Wiley Online Library
The present study evaluated, via a combined electrophysiological and dialysis approach, the
potential influence of serotonin (5‐HT) 2C as compared to 5‐HT 2A and 5‐HT 2B receptors …
potential influence of serotonin (5‐HT) 2C as compared to 5‐HT 2A and 5‐HT 2B receptors …
Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of α2‐adrenergic and serotonin2C …
…, JM Rivet, A Adhumeau‐Auclair… - European Journal of …, 2000 - Wiley Online Library
Mirtazapine displayed marked affinity for cloned, human α 2A ‐adrenergic (AR) receptors at
which it blocked noradrenaline (NA)‐induced stimulation of guanosine‐5′‐O‐(3‐[ 35 S]thio)…
which it blocked noradrenaline (NA)‐induced stimulation of guanosine‐5′‐O‐(3‐[ 35 S]thio)…
The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels …
A Dekeyne, M Brocco, A Adhumeau, A Gobert… - …, 2000 - Springer
Rationale: The benzodioxane, S15535, possesses low intrinsic activity and marked selectivity
at 5-HT 1A receptors, hippocampal populations of which are implicated in anxious states. …
at 5-HT 1A receptors, hippocampal populations of which are implicated in anxious states. …
S18327 (1-{2-[4-(6-Fluoro-1, 2-benzisoxazol-3-yl) piperid-1-yl] ethyl} 3-phenyl imidazolin-2-one), a Novel, Potential Antipsychotic Displaying Marked Antagonist …
…, D Cussac, JM Rivet, V Audinot, A Adhumeau… - … of Pharmacology and …, 2000 - ASPET
S18327 displayed modest affinity for human (h)D 2 and hD 3 receptors and high affinity for
hD 4 receptors. At each, S18327 antagonized stimulation of [ 35 S]guanosine-5′-O-(3-thio)…
hD 4 receptors. At each, S18327 antagonized stimulation of [ 35 S]guanosine-5′-O-(3-thio)…
[PDF][PDF] S 18327, a novel phenylimidazolinone and potential antipsychotic: Antagonist properties at α2-adrenergic (AR) receptors in vitro and in vivo
…, A Newman-Tancredi, A Adhumeau… - European …, 1999 - academia.edu
Results: We found significantly increased perfusion values in the leg low frontal cortical region
after 6-week olanzapine treatment compared to the drug-free values (Z= 2.83, p< 0.05). …
after 6-week olanzapine treatment compared to the drug-free values (Z= 2.83, p< 0.05). …
[PDF][PDF] … -TANCREDI, FRANC OISE LEJEUNE, DIDIER CUSSAC, JEAN-MICHEL RIVET, VALÉRIE AUDINOT, AGNES ADHUMEAU, MAURICETTE BROCCO, JEAN …
JA BOUTIN, N DESPAUX, JL PEGLION - THE JOURNAL OF …, 2000 - Citeseer
S18327 displayed modest affinity for human (h) D2 and hD3 receptors and high affinity for
hD4 receptors. At each, S18327 antagonized stimulation of [35S] guanosine-5-O-(3-thio) …
hD4 receptors. At each, S18327 antagonized stimulation of [35S] guanosine-5-O-(3-thio) …
Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade
MJ Millan, M Brocco, A Gobert, A Dekeyne - Psychopharmacology, 2005 - Springer
Rationale The novel antidepressant agent, agomelatine, behaves as an agonist at melatonin
receptors and as an antagonist at serotonin (5-HT) 2C receptors. Objectives To determine …
receptors and as an antagonist at serotonin (5-HT) 2C receptors. Objectives To determine …
The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical …
MJ Millan, A Gobert, F Lejeune, A Dekeyne… - … of Pharmacology and …, 2003 - ASPET
Agomelatine (S20098) displayed pK i values of 6.4 and 6.2 at native (porcine) and cloned,
human (h)5-hydroxytryptamine (5-HT) 2C receptors, respectively. It also interacted with h5-HT …
human (h)5-hydroxytryptamine (5-HT) 2C receptors, respectively. It also interacted with h5-HT …
On the role of serotonin2A-2C receptors in the sensitization to cocaine
M Filip, E Nowak, I Papla - Journal of Physiology and Pharmacology, 2001 - agro.icm.edu.pl
Apart from showing involvement oi ‘dopamine, recent studies also indicate a role of serotonin
[5-HT) in the behavioral elfects of cocaine in rodents. In the present study we investigated …
[5-HT) in the behavioral elfects of cocaine in rodents. In the present study we investigated …
Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions
BP Guiard, M El Mansari, Z Merali… - International Journal of …, 2008 - academic.oup.com
Anatomical studies have established the existence of reciprocal relationships between the
main population of monoamine, serotonin (5-HT), norepinephrine (NE) and dopamine (DA) …
main population of monoamine, serotonin (5-HT), norepinephrine (NE) and dopamine (DA) …