[HTML][HTML] Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTR Mutation

…, JM Pilewski, RC Rubenstein, AZ Uluer… - … England Journal of …, 2010 - Mass Medical Soc
Background A new approach in the treatment of cystic fibrosis involves improving the function
of mutant cystic fibrosis transmembrane conductance regulator (CFTR). VX-770, a CFTR …

Issues affecting young people with asthma through the transition period to adult care

PD Robinson, G Jayasuriya, S Haggie, AZ Uluer… - Paediatric Respiratory …, 2022 - Elsevier
Asthma is among the most common medical conditions affecting children and young people,
with adolescence a recognised period of increased risk, overrepresented in analyses …

[HTML][HTML] Safety and efficacy of vanzacaftor–tezacaftor–deutivacaftor in adults with cystic fibrosis: randomised, double-blind, controlled, phase 2 trials

AZ Uluer, G MacGregor, P Azevedo… - The Lancet …, 2023 - thelancet.com
Background Elexacaftor–tezacaftor–ivacaftor has been shown to be safe and efficacious in
people with cystic fibrosis and at least one F508del allele. Our aim was to identify a novel …

[HTML][HTML] A safe protocol for rapid desensitization in patients with cystic fibrosis and antibiotic hypersensitivity

HJ Legere III, RI Palis, TR Bouza, AZ Uluer… - Journal of Cystic …, 2009 - Elsevier
BACKGROUND: CF patients often demonstrate hypersensitivity to one or multiple antibiotics
due to frequent and repeated exposures. Attempts at antibiotic desensitization in this …

High-affinity agonist binding is not sufficient for agonist efficacy at 5-hydroxytryptamine2A receptors: evidence in favor of a modified ternary complex model

BL Roth, MS Choudhary, N Khan, AZ Uluer - Journal of Pharmacology and …, 1997 - ASPET
In this study, the relationship between high-affinity agonist binding and second messenger
production was examined at native and mutant 5-hydroxytryptamine 2A receptors. At native 5-…

An automated integrated platform for rapid and sensitive multiplexed protein profiling using human saliva samples

…, JP Alarie, Y Wu, FG Oppenheim, FF Little, AZ Uluer… - Lab on a Chip, 2014 - pubs.rsc.org
During the last decade, saliva has emerged as a potentially ideal diagnostic biofluid for
noninvasive testing. In this paper, we present an automated, integrated platform useable by …

Recovery of Herbaspirillum Species from Persons with Cystic Fibrosis

T Spilker, AZ Uluer, FM Marty, WW Yeh… - Journal of clinical …, 2008 - Am Soc Microbiol
Herbaspirillum species are not known to be human pathogens. We report on the identification
of Herbaspirillum from cultures from 28 persons with cystic fibrosis (CF). Most isolates …

[HTML][HTML] Cystic fibrosis-related mortality in the United States from 1999 to 2020: an observational analysis of time trends and disparities

…, J Shalhoub, JS Kurman, R Nanchal, AZ Uluer… - Scientific Reports, 2023 - nature.com
Cystic fibrosis transmembrane conductance regulator modulators have revolutionized cystic
fibrosis (CF) care in the past decade. This study explores the CF-related mortality trends in …

Lymphomatoid papulosis and associated cutaneous lymphoproliferative disorders exhibit a common clonal origin

GS Wood, CF Crooks, AZ Uluer - Journal of investigative dermatology, 1995 - Elsevier
Determination of the clonal relationship among multiple lymphoproliferative disorders
occurring in individual patients has been hampered by dependence on molecular biologic …

A pilot study of inspiratory muscle training to improve exercise capacity in patients with Fontan physiology

…, KM Shafer, AM Valente, AZ Uluer… - Seminars in Thoracic …, 2018 - Elsevier
While the Fontan procedure has improved life expectancy, patients with single ventricle
physiology have impaired exercise capacity due to limited increase in pulmonary blood flow …