Molecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine
LE Pomeranz, AE Reynolds… - … and molecular biology …, 2005 - Am Soc Microbiol
Pseudorabies virus (PRV) is a herpesvirus of swine, a member of the Alphaherpesvirinae
subfamily, and the etiological agent of Aujeszky's disease. This review describes the …
subfamily, and the etiological agent of Aujeszky's disease. This review describes the …
[HTML][HTML] Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions
NS Vasudev, AR Reynolds - Angiogenesis, 2014 - Springer
Tumours require a vascular supply to grow and can achieve this via the expression of pro-angiogenic
growth factors, including members of the vascular endothelial growth factor (VEGF…
growth factors, including members of the vascular endothelial growth factor (VEGF…
Emerging roles for p120-catenin in cell adhesion and cancer
AB Reynolds, A Roczniak-Ferguson - Oncogene, 2004 - nature.com
… , p120 tyrosine phosphorylation does not appear to be essential for Src-induced transformation,
as p120 siRNA knockdown cell lines can be transformed efficiently by Src (A Reynolds, …
as p120 siRNA knockdown cell lines can be transformed efficiently by Src (A Reynolds, …
[HTML][HTML] Functional siRNAs and miRNAs exhibit strand bias
A Khvorova, A Reynolds, SD Jayasena - Cell, 2003 - cell.com
Both microRNAs (miRNA) and small interfering RNAs (siRNA) share a common set of cellular
proteins (Dicer and the RNA-induced silencing complex [RISC]) to elicit RNA interference. …
proteins (Dicer and the RNA-induced silencing complex [RISC]) to elicit RNA interference. …
[HTML][HTML] The accessible chromatin landscape of the human genome
…, AP Reynolds, V Roach, A Safi, ME Sanchez, A Sanyal… - Nature, 2012 - nature.com
DNase I hypersensitive sites (DHSs) are markers of regulatory DNA and have underpinned
the discovery of all classes of cis-regulatory elements including enhancers, promoters, …
the discovery of all classes of cis-regulatory elements including enhancers, promoters, …
Systematic localization of common disease-associated variation in regulatory DNA
Genome-wide association studies have identified many noncoding variants associated with
common diseases and traits. We show that these variants are concentrated in regulatory …
common diseases and traits. We show that these variants are concentrated in regulatory …
[HTML][HTML] An expansive human regulatory lexicon encoded in transcription factor footprints
Regulatory factor binding to genomic DNA protects the underlying sequence from cleavage
by DNase I, leaving nucleotide-resolution footprints. Using genomic DNase I footprinting …
by DNase I, leaving nucleotide-resolution footprints. Using genomic DNase I footprinting …
BEDOPS: high-performance genomic feature operations
S Neph, MS Kuehn, AP Reynolds, E Haugen… - …, 2012 - academic.oup.com
The large and growing number of genome-wide datasets highlights the need for high-performance
feature analysis and data comparison methods, in addition to efficient data storage …
feature analysis and data comparison methods, in addition to efficient data storage …
Global mapping of protein-DNA interactions in vivo by digital genomic footprinting
The orchestrated binding of transcriptional activators and repressors to specific DNA sequences
in the context of chromatin defines the regulatory program of eukaryotic genomes. We …
in the context of chromatin defines the regulatory program of eukaryotic genomes. We …
[HTML][HTML] Cell-of-origin chromatin organization shapes the mutational landscape of cancer
Cancer is a disease potentiated by mutations in somatic cells. Cancer mutations are not
distributed uniformly along the human genome. Instead, different human genomic regions vary …
distributed uniformly along the human genome. Instead, different human genomic regions vary …