Amphetamine is a psychostimulant commonly used to treat several disorders, including
attention deficit, narcolepsy, and obesity. Plasmalemmal and vesicular monoamine transporters, …

Synthetic cathinones are an emerging class of designer drugs abused for psychostimulant
and hallucinogenic effects similar to cocaine, methylenedioxymethamphetamine (MDMA), or …

The designer stimulant 4-methylmethcathinone (mephedrone) is among the most popular of
the derivatives of the naturally occurring psychostimulant cathinone. Mephedrone has been …

Many psychostimulants alter plasmalemmal monoaminergic transporter function. Some,
such as cocaine, prevent the reuptake of newly released dopamine, serotonin or …

Dopamine (DA) plays a well recognized role in a variety of physiologic functions such as
movement, cognition, mood, and reward. Consequently, many human disorders are due, in part…

Background Despite widespread use of methamphetamine and other amphetamine-type
stimulants (METH/AMPH), little is known about the long-term medical consequences of METH/…

… Kokoshka JM , Vaughan RA , Hanson GR , Fleckenstein AE . Nature of methamphetamine-…
Baucum AJ, 2nd , Rau KS , Riddle EL , Hanson GR , Fleckenstein AE . Methamphetamine …

Vesicular sequestration is important in the regulation of cytoplasmic concentrations of
monoamines such as dopamine. Moreover, recent evidence suggests that increases in …

Reactive oxygen species decrease dopamine transporter (DAT) functionin vitro. Because of
this, and the finding that METH administration causes oxygen radical formation in vivo, the …

The plasmalemmal dopamine (DA) transporter (DAT) is a principal site of action for cocaine.
This report presents the novel finding that in addition to inhibiting DAT function, cocaine …