Similar articles for PMID: 18218832

Year	Number of Results
1948	1
1955	2
1958	2
1962	1
1986	1
1987	1
1990	4
1991	1
1992	1
1993	3
1996	5
1997	1
1998	2
1999	1
2001	2
2002	3
2003	3
2004	6
2005	5
2006	10
2007	21
2008	22
2009	15
2010	8
2011	2
2012	5
2013	15
2014	7
2015	6
2016	3
2017	6
2018	5
2019	2
2020	4
2022	3
2024	0

1

Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease.

Hirsh AJ, Zhang J, Zamurs A, Fleegle J, Thelin WR, Caldwell RA, Sabater JR, Abraham WM, Donowitz M, Cha B, Johnson KB, St George JA, Johnson MR, Boucher RC. Hirsh AJ, et al. J Pharmacol Exp Ther. 2008 Apr;325(1):77-88. doi: 10.1124/jpet.107.130443. Epub 2008 Jan 24. J Pharmacol Exp Ther. 2008. PMID: 18218832

2

Evaluation of second generation amiloride analogs as therapy for cystic fibrosis lung disease.

Hirsh AJ, Sabater JR, Zamurs A, Smith RT, Paradiso AM, Hopkins S, Abraham WM, Boucher RC. Hirsh AJ, et al. J Pharmacol Exp Ther. 2004 Dec;311(3):929-38. doi: 10.1124/jpet.104.071886. Epub 2004 Jul 23. J Pharmacol Exp Ther. 2004. PMID: 15273255

3

Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis.

Hirsh AJ, Molino BF, Zhang J, Astakhova N, Geiss WB, Sargent BJ, Swenson BD, Usyatinsky A, Wyle MJ, Boucher RC, Smith RT, Zamurs A, Johnson MR. Hirsh AJ, et al. J Med Chem. 2006 Jul 13;49(14):4098-115. doi: 10.1021/jm051134w. J Med Chem. 2006. PMID: 16821771

4

Role of the amiloride-sensitive epithelial Na+ channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease.

Mall MA. Mall MA. Exp Physiol. 2009 Feb;94(2):171-4. doi: 10.1113/expphysiol.2008.042994. Epub 2008 Dec 5. Exp Physiol. 2009. PMID: 19060118 Free article.

5

Specific inhibition of epithelial Na+ channels by antisense oligonucleotides for the treatment of Na+ hyperabsorption in cystic fibrosis.

Sobczak K, Segal A, Bangel-Ruland N, Semmler J, Van Driessche W, Lindemann H, Heermann R, Weber WM. Sobczak K, et al. J Gene Med. 2009 Sep;11(9):813-23. doi: 10.1002/jgm.1363. J Gene Med. 2009. PMID: 19533590

6

Interleukin-1beta suppresses epithelial sodium channel beta-subunit expression and ENaC-dependent fluid absorption in human middle ear epithelial cells.

Choi JY, Choi YS, Kim SJ, Son EJ, Choi HS, Yoon JH. Choi JY, et al. Eur J Pharmacol. 2007 Jul 12;567(1-2):19-25. doi: 10.1016/j.ejphar.2007.04.026. Epub 2007 Apr 22. Eur J Pharmacol. 2007. PMID: 17499239

7

Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways.

Reihill JA, Walker B, Hamilton RA, Ferguson TE, Elborn JS, Stutts MJ, Harvey BJ, Saint-Criq V, Hendrick SM, Martin SL. Reihill JA, et al. Am J Respir Crit Care Med. 2016 Sep 15;194(6):701-10. doi: 10.1164/rccm.201511-2216OC. Am J Respir Crit Care Med. 2016. PMID: 27014936

8

N-acetylcysteine inhibits Na+ absorption across human nasal epithelial cells.

Rochat T, Lacroix JS, Jornot L. Rochat T, et al. J Cell Physiol. 2004 Oct;201(1):106-16. doi: 10.1002/jcp.20066. J Cell Physiol. 2004. PMID: 15281093

9

Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway.

Zhang LN, Karp P, Gerard CJ, Pastor E, Laux D, Munson K, Yan Z, Liu X, Godwin S, Thomas CP, Zabner J, Shi H, Caldwell CW, Peluso R, Carter B, Engelhardt JF. Zhang LN, et al. Mol Ther. 2004 Dec;10(6):990-1002. doi: 10.1016/j.ymthe.2004.08.009. Mol Ther. 2004. PMID: 15564131 Free article.

10

Parallel improvement of sodium and chloride transport defects by miglustat (n-butyldeoxynojyrimicin) in cystic fibrosis epithelial cells.

Noël S, Wilke M, Bot AG, De Jonge HR, Becq F. Noël S, et al. J Pharmacol Exp Ther. 2008 Jun;325(3):1016-23. doi: 10.1124/jpet.107.135582. Epub 2008 Feb 28. J Pharmacol Exp Ther. 2008. PMID: 18309088

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