Similar articles for PMID: 15159443

Year	Number of Results
1991	1
1993	1
1994	3
1995	1
1996	7
1997	9
1998	4
1999	5
2000	5
2001	5
2002	6
2003	6
2004	6
2005	6
2006	4
2007	6
2009	1
2010	3
2011	2
2012	4
2013	7
2014	4
2015	2
2016	4
2017	3
2018	1
2019	4
2020	2
2021	4
2022	3
2023	5
2024	0

1

Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6.

Desta Z, Ward BA, Soukhova NV, Flockhart DA. Desta Z, et al. J Pharmacol Exp Ther. 2004 Sep;310(3):1062-75. doi: 10.1124/jpet.104.065607. Epub 2004 May 24. J Pharmacol Exp Ther. 2004. PMID: 15159443

2

Comparative metabolic study between two selective estrogen receptor modulators, toremifene and tamoxifen, in human liver microsomes.

Watanabe M, Watanabe N, Maruyama S, Kawashiro T. Watanabe M, et al. Drug Metab Pharmacokinet. 2015 Oct;30(5):325-33. doi: 10.1016/j.dmpk.2015.05.004. Epub 2015 May 29. Drug Metab Pharmacokinet. 2015. PMID: 26423799

3

The interactions of a selective protein kinase C beta inhibitor with the human cytochromes P450.

Ring BJ, Gillespie JS, Binkley SN, Campanale KM, Wrighton SA. Ring BJ, et al. Drug Metab Dispos. 2002 Sep;30(9):957-61. doi: 10.1124/dmd.30.9.957. Drug Metab Dispos. 2002. PMID: 12167559

4

CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver.

Dehal SS, Kupfer D. Dehal SS, et al. Cancer Res. 1997 Aug 15;57(16):3402-6. Cancer Res. 1997. PMID: 9270005

5

Cytochrome P-450 3A and 2D6 catalyze ortho hydroxylation of 4-hydroxytamoxifen and 3-hydroxytamoxifen (droloxifene) yielding tamoxifen catechol: involvement of catechols in covalent binding to hepatic proteins.

Dehal SS, Kupfer D. Dehal SS, et al. Drug Metab Dispos. 1999 Jun;27(6):681-8. Drug Metab Dispos. 1999. PMID: 10348797

6

Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7.

Williams JA, Ring BJ, Cantrell VE, Jones DR, Eckstein J, Ruterbories K, Hamman MA, Hall SD, Wrighton SA. Williams JA, et al. Drug Metab Dispos. 2002 Aug;30(8):883-91. doi: 10.1124/dmd.30.8.883. Drug Metab Dispos. 2002. PMID: 12124305

7

Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: formation of the 4-hydroxy, 4'-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen.

Crewe HK, Notley LM, Wunsch RM, Lennard MS, Gillam EM. Crewe HK, et al. Drug Metab Dispos. 2002 Aug;30(8):869-74. doi: 10.1124/dmd.30.8.869. Drug Metab Dispos. 2002. PMID: 12124303

8

Characterization of the biotransformation pathways of clomiphene, tamoxifen and toremifene as assessed by LC-MS/(MS) following in vitro and excretion studies.

Mazzarino M, Biava M, de la Torre X, Fiacco I, Botrè F. Mazzarino M, et al. Anal Bioanal Chem. 2013 Jun;405(16):5467-87. doi: 10.1007/s00216-013-6961-7. Epub 2013 Apr 23. Anal Bioanal Chem. 2013. PMID: 23604525

9

Metabolism of the active metabolite of quetiapine, N-desalkylquetiapine in vitro.

Bakken GV, Molden E, Knutsen K, Lunder N, Hermann M. Bakken GV, et al. Drug Metab Dispos. 2012 Sep;40(9):1778-84. doi: 10.1124/dmd.112.045237. Epub 2012 Jun 11. Drug Metab Dispos. 2012. PMID: 22688609

10

Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin.

Parte P, Kupfer D. Parte P, et al. Drug Metab Dispos. 2005 Oct;33(10):1446-52. doi: 10.1124/dmd.104.000802. Epub 2005 Jun 29. Drug Metab Dispos. 2005. PMID: 15987777

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

116 results

Results by year