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Page 1
Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors.
J Pharmacol Exp Ther. 1998 Oct;287(1):198-207.
J Pharmacol Exp Ther. 1998.
PMID: 9765338
Synthesis and in vitro activity of 3 beta-substituted-3 alpha-hydroxypregnan-20-ones: allosteric modulators of the GABAA receptor.
Hogenkamp DJ, Tahir SH, Hawkinson JE, Upasani RB, Alauddin M, Kimbrough CL, Acosta-Burruel M, Whittemore ER, Woodward RM, Lan NC, Gee KW, Bolger MB.
Hogenkamp DJ, et al. Among authors: upasani rb.
J Med Chem. 1997 Jan 3;40(1):61-72. doi: 10.1021/jm960021x.
J Med Chem. 1997.
PMID: 9016329
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Structure-activity relationship for a series of 2-substituted 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indoles: potent subtype-selective inhibitors of N-methyl-D-aspartate (NMDA) receptors.
Tamiz AP, Whittemore ER, Woodward RM, Upasani RB, Keana JF.
Tamiz AP, et al. Among authors: upasani rb.
Bioorg Med Chem Lett. 1999 Jun 7;9(11):1619-24. doi: 10.1016/s0960-894x(99)00248-6.
Bioorg Med Chem Lett. 1999.
PMID: 10386947
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3 alpha-Hydroxy-3 beta-(phenylethynyl)-5 beta-pregnan-20-ones: synthesis and pharmacological activity of neuroactive steroids with high affinity for GABAA receptors.
Upasani RB, Yang KC, Acosta-Burruel M, Konkoy CS, McLellan JA, Woodward RM, Lan NC, Carter RB, Hawkinson JE.
Upasani RB, et al.
J Med Chem. 1997 Jan 3;40(1):73-84. doi: 10.1021/jm9605344.
J Med Chem. 1997.
PMID: 9016330
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