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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 2
2004 1
2005 1
2008 1
2013 1
2014 2
2015 2
2016 1
2017 1
2020 3
2023 2
2024 1

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18 results

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Page 1
Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Thompson AA, Harbut MB, Kung PP, Karpowich NK, Branson JD, Grant JC, Hagan D, Pascual HA, Bai G, Zavareh RB, Coate HR, Collins BC, Côte M, Gelin CF, Damm-Ganamet KL, Gholami H, Huff AR, Limon L, Lumb KJ, Mak PA, Nakafuku KM, Price EV, Shih AY, Tootoonchi M, Vellore NA, Wang J, Wei N, Ziff J, Berger SB, Edwards JP, Gardet A, Sun S, Towne JE, Venable JD, Shi Z, Venkatesan H, Rives ML, Sharma S, Shireman BT, Allen SJ. Thompson AA, et al. Among authors: shireman bt. Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2216342120. doi: 10.1073/pnas.2216342120. Epub 2023 Apr 25. Proc Natl Acad Sci U S A. 2023. PMID: 37098070 Free PMC article.
Selective orexin receptor antagonists.
Lebold TP, Bonaventure P, Shireman BT. Lebold TP, et al. Among authors: shireman bt. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4761-9. doi: 10.1016/j.bmcl.2013.06.057. Epub 2013 Jul 4. Bioorg Med Chem Lett. 2013. PMID: 23891187 Review.
Copper-mediated synthesis of drug-like bicyclopentanes.
Zhang X, Smith RT, Le C, McCarver SJ, Shireman BT, Carruthers NI, MacMillan DWC. Zhang X, et al. Among authors: shireman bt. Nature. 2020 Apr;580(7802):220-226. doi: 10.1038/s41586-020-2060-z. Epub 2020 Feb 17. Nature. 2020. PMID: 32066140 Free PMC article.
Substituted 5,6-(Dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-methanones as P2X7 Antagonists.
Ziff J, Rudolph DA, Stenne B, Koudriakova T, Lord B, Bonaventure P, Lovenberg TW, Carruthers NI, Bhattacharya A, Letavic MA, Shireman BT. Ziff J, et al. Among authors: shireman bt. ACS Chem Neurosci. 2016 Apr 20;7(4):498-504. doi: 10.1021/acschemneuro.5b00304. Epub 2016 Jan 19. ACS Chem Neurosci. 2016. PMID: 26754558
Development of small molecule inhibitors of natural killer group 2D receptor (NKG2D).
Wang J, Nakafuku KM, Ziff J, Gelin CF, Gholami H, Thompson AA, Karpowich NK, Limon L, Coate HR, Damm-Ganamet KL, Shih AY, Grant JC, Côte M, Mak PA, Pascual HA, Rives ML, Edwards JP, Venable JD, Venkatesan H, Shi Z, Allen SJ, Sharma S, Kung PP, Shireman BT. Wang J, et al. Among authors: shireman bt. Bioorg Med Chem Lett. 2023 Nov 15;96:129492. doi: 10.1016/j.bmcl.2023.129492. Epub 2023 Sep 29. Bioorg Med Chem Lett. 2023. PMID: 37778428
Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793.
Préville C, Bonaventure P, Koudriakova T, Lord B, Nepomuceno D, Rizzolio M, Mani N, Coe KJ, Ndifor A, Dugovic C, Dvorak CA, Coate H, Pippel DJ, Fitzgerald A, Allison B, Lovenberg TW, Carruthers NI, Shireman BT. Préville C, et al. Among authors: shireman bt. ACS Med Chem Lett. 2020 Apr 27;11(10):2002-2009. doi: 10.1021/acsmedchemlett.0c00085. eCollection 2020 Oct 8. ACS Med Chem Lett. 2020. PMID: 33062185 Free PMC article.
Novel Octahydropyrrolo[3,4-c]pyrroles Are Selective Orexin-2 Antagonists: SAR Leading to a Clinical Candidate.
Letavic MA, Bonaventure P, Carruthers NI, Dugovic C, Koudriakova T, Lord B, Lovenberg TW, Ly KS, Mani NS, Nepomuceno D, Pippel DJ, Rizzolio M, Shelton JE, Shah CR, Shireman BT, Young LK, Yun S. Letavic MA, et al. Among authors: shireman bt. J Med Chem. 2015 Jul 23;58(14):5620-36. doi: 10.1021/acs.jmedchem.5b00742. Epub 2015 Jul 8. J Med Chem. 2015. PMID: 26087021
Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans.
Salvadore G, Bonaventure P, Shekhar A, Johnson PL, Lord B, Shireman BT, Lebold TP, Nepomuceno D, Dugovic C, Brooks S, Zuiker R, Bleys C, Tatikola K, Remmerie B, Jacobs GE, Schruers K, Moyer J, Nash A, Van Nueten LGM, Drevets WC. Salvadore G, et al. Among authors: shireman bt. Transl Psychiatry. 2020 Sep 7;10(1):308. doi: 10.1038/s41398-020-00937-9. Transl Psychiatry. 2020. PMID: 32895369 Free PMC article.
A selective orexin-1 receptor antagonist attenuates stress-induced hyperarousal without hypnotic effects.
Bonaventure P, Yun S, Johnson PL, Shekhar A, Fitz SD, Shireman BT, Lebold TP, Nepomuceno D, Lord B, Wennerholm M, Shelton J, Carruthers N, Lovenberg T, Dugovic C. Bonaventure P, et al. Among authors: shireman bt. J Pharmacol Exp Ther. 2015 Mar;352(3):590-601. doi: 10.1124/jpet.114.220392. Epub 2015 Jan 12. J Pharmacol Exp Ther. 2015. PMID: 25583879 Free PMC article.
18 results