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Year Number of Results
1997 1
1998 1
2015 3
2018 3
2019 2
2020 6
2021 2
2023 2
2024 1

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21 results

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Page 1
Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD.
Basu S, Shukron O, Hall D, Parutto P, Ponjavic A, Shah D, Boucher W, Lando D, Zhang W, Reynolds N, Sober LH, Jartseva A, Ragheb R, Ma X, Cramard J, Floyd R, Balmer J, Drury TA, Carr AR, Needham LM, Aubert A, Communie G, Gor K, Steindel M, Morey L, Blanco E, Bartke T, Di Croce L, Berger I, Schaffitzel C, Lee SF, Stevens TJ, Klenerman D, Hendrich BD, Holcman D, Laue ED. Basu S, et al. Among authors: needham lm. Nat Struct Mol Biol. 2023 Nov;30(11):1628-1639. doi: 10.1038/s41594-023-01095-4. Epub 2023 Sep 28. Nat Struct Mol Biol. 2023. PMID: 37770717 Free PMC article.
Label-free observation of individual solution phase molecules.
Needham LM, Saavedra C, Rasch JK, Sole-Barber D, Schweitzer BS, Fairhall AJ, Vollbrecht CH, Mehlenbacher B, Zhang Z, Tenbrake L, Pfeifer H, Chapman ER, Goldsmith RH. Needham LM, et al. bioRxiv [Preprint]. 2023 Mar 25:2023.03.24.534170. doi: 10.1101/2023.03.24.534170. bioRxiv. 2023. PMID: 36993572 Free PMC article. Preprint.
vLUME: 3D virtual reality for single-molecule localization microscopy.
Spark A, Kitching A, Esteban-Ferrer D, Handa A, Carr AR, Needham LM, Ponjavic A, Santos AM, McColl J, Leterrier C, Davis SJ, Henriques R, Lee SF. Spark A, et al. Among authors: needham lm. Nat Methods. 2020 Nov;17(11):1097-1099. doi: 10.1038/s41592-020-0962-1. Epub 2020 Oct 12. Nat Methods. 2020. PMID: 33046895 Free PMC article.
Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization.
Müller KH, Hayward R, Rajan R, Whitehead M, Cobb AM, Ahmad S, Sun M, Goldberga I, Li R, Bashtanova U, Puszkarska AM, Reid DG, Brooks RA, Skepper JN, Bordoloi J, Chow WY, Oschkinat H, Groombridge A, Scherman OA, Harrison JA, Verhulst A, D'Haese PC, Neven E, Needham LM, Lee SF, Shanahan CM, Duer MJ. Müller KH, et al. Among authors: needham lm. Cell Rep. 2019 Jun 11;27(11):3124-3138.e13. doi: 10.1016/j.celrep.2019.05.038. Cell Rep. 2019. PMID: 31189100 Free PMC article.
Single-molecule fluorescence detection of a tricyclic nucleoside analogue.
Samaan GN, Wyllie MK, Cizmic JM, Needham LM, Nobis D, Ngo K, Andersen S, Magennis SW, Lee SF, Purse BW. Samaan GN, et al. Among authors: needham lm. Chem Sci. 2020 Dec 28;12(7):2623-2628. doi: 10.1039/d0sc03903a. Chem Sci. 2020. PMID: 34164030 Free PMC article.
Single-molecule visualization of DNA G-quadruplex formation in live cells.
Di Antonio M, Ponjavic A, Radzevičius A, Ranasinghe RT, Catalano M, Zhang X, Shen J, Needham LM, Lee SF, Klenerman D, Balasubramanian S. Di Antonio M, et al. Among authors: needham lm. Nat Chem. 2020 Sep;12(9):832-837. doi: 10.1038/s41557-020-0506-4. Epub 2020 Jul 20. Nat Chem. 2020. PMID: 32690897 Free PMC article.
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers.
Aprile FA, Sormanni P, Podpolny M, Chhangur S, Needham LM, Ruggeri FS, Perni M, Limbocker R, Heller GT, Sneideris T, Scheidt T, Mannini B, Habchi J, Lee SF, Salinas PC, Knowles TPJ, Dobson CM, Vendruscolo M. Aprile FA, et al. Among authors: needham lm. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13509-13518. doi: 10.1073/pnas.1919464117. Epub 2020 Jun 3. Proc Natl Acad Sci U S A. 2020. PMID: 32493749 Free PMC article.
ThX - a next-generation probe for the early detection of amyloid aggregates.
Needham LM, Weber J, Varela JA, Fyfe JWB, Do DT, Xu CK, Tutton L, Cliffe R, Keenlyside B, Klenerman D, Dobson CM, Hunter CA, Müller KH, O'Holleran K, Bohndiek SE, Snaddon TN, Lee SF. Needham LM, et al. Chem Sci. 2020 Feb 21;11(18):4578-4583. doi: 10.1039/c9sc04730a. Chem Sci. 2020. PMID: 34122915 Free PMC article.
21 results