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2004 2
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2009 1
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Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Kato N, Comer E, Sakata-Kato T, Sharma A, Sharma M, Maetani M, Bastien J, Brancucci NM, Bittker JA, Corey V, Clarke D, Derbyshire ER, Dornan GL, Duffy S, Eckley S, Itoe MA, Koolen KM, Lewis TA, Lui PS, Lukens AK, Lund E, March S, Meibalan E, Meier BC, McPhail JA, Mitasev B, Moss EL, Sayes M, Van Gessel Y, Wawer MJ, Yoshinaga T, Zeeman AM, Avery VM, Bhatia SN, Burke JE, Catteruccia F, Clardy JC, Clemons PA, Dechering KJ, Duvall JR, Foley MA, Gusovsky F, Kocken CH, Marti M, Morningstar ML, Munoz B, Neafsey DE, Sharma A, Winzeler EA, Wirth DF, Scherer CA, Schreiber SL. Kato N, et al. Among authors: mitasev b. Nature. 2016 Oct 20;538(7625):344-349. doi: 10.1038/nature19804. Epub 2016 Sep 7. Nature. 2016. PMID: 27602946 Free PMC article.
Total synthesis of plukenetione A.
Zhang Q, Mitasev B, Qi J, Porco JA Jr. Zhang Q, et al. Among authors: mitasev b. J Am Chem Soc. 2010 Oct 13;132(40):14212-5. doi: 10.1021/ja105784s. J Am Chem Soc. 2010. PMID: 20843036 Free PMC article.
Synthesis and biological evaluation of ABCD ring fragments of the kibdelones.
Sloman DL, Mitasev B, Scully SS, Beutler JA, Porco JA Jr. Sloman DL, et al. Among authors: mitasev b. Angew Chem Int Ed Engl. 2011 Mar 7;50(11):2511-5. doi: 10.1002/anie.201007613. Epub 2011 Feb 18. Angew Chem Int Ed Engl. 2011. PMID: 21370327 Free PMC article. No abstract available.
Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase 1a/b trial.
Gaur AH, McCarthy JS, Panetta JC, Dallas RH, Woodford J, Tang L, Smith AM, Stewart TB, Branum KC, Freeman BB 3rd, Patel ND, John E, Chalon S, Ost S, Heine RN, Richardson JL, Christensen R, Flynn PM, Van Gessel Y, Mitasev B, Möhrle JJ, Gusovsky F, Bebrevska L, Guy RK. Gaur AH, et al. Among authors: mitasev b. Lancet Infect Dis. 2020 Aug;20(8):964-975. doi: 10.1016/S1473-3099(19)30611-5. Epub 2020 Apr 8. Lancet Infect Dis. 2020. PMID: 32275867 Clinical Trial.
12 results