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1988 1
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Page 1
Targeting aldehyde dehydrogenase: a potential approach for cell labeling.
Vaidyanathan G, Song H, Affleck D, McDougald DL, Storms RW, Zalutsky MR, Chin BB. Vaidyanathan G, et al. Among authors: mcdougald dl. Nucl Med Biol. 2009 Nov;36(8):919-29. doi: 10.1016/j.nucmedbio.2009.08.001. Epub 2009 Oct 3. Nucl Med Biol. 2009. PMID: 19875048 Free PMC article.
Structure-based design of potent retinoid X receptor alpha agonists.
Haffner CD, Lenhard JM, Miller AB, McDougald DL, Dwornik K, Ittoop OR, Gampe RT Jr, Xu HE, Blanchard S, Montana VG, Consler TG, Bledsoe RK, Ayscue A, Croom D. Haffner CD, et al. Among authors: mcdougald dl. J Med Chem. 2004 Apr 8;47(8):2010-29. doi: 10.1021/jm030565g. J Med Chem. 2004. PMID: 15056000
2-Cyano-4-fluoro-1-thiovalylpyrrolidine analogues as potent inhibitors of DPP-IV.
Haffner CD, McDougald DL, Reister SM, Thompson BD, Conlee C, Fang J, Bass J, Lenhard JM, Croom D, Secosky-Chang MB, Tomaszek T, McConn D, Wells-Knecht K, Johnson PR. Haffner CD, et al. Among authors: mcdougald dl. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5257-61. doi: 10.1016/j.bmcl.2005.08.050. Epub 2005 Sep 15. Bioorg Med Chem Lett. 2005. PMID: 16168640
CYP3A induction by N-hydroxyformamide tumor necrosis factor-alpha converting enzyme/matrix metalloproteinase inhibitors use of a pregname X receptor activation assay and primary hepatocyte culture for assessing induction potential in humans.
Tippin TK, Hamilton G, Moore L, Beaudet EJ, Jolley S, Brodie TA, Andrews RC, Becherer JD, McDougald DL, Gaul MD, Hoivik DJ, Mellon-Kusibab K, Lehmann J, Kliewer S, Novick S, Laethem R, Zhao Z, LeCluyse EL. Tippin TK, et al. Among authors: mcdougald dl. Drug Metab Dispos. 2003 Jul;31(7):870-7. doi: 10.1124/dmd.31.7.870. Drug Metab Dispos. 2003. PMID: 12814963
Substrate specificity and novel selective inhibitors of TNF-alpha converting enzyme (TACE) from two-dimensional substrate mapping.
Lambert MH, Blackburn RK, Seaton TD, Kassel DB, Kinder DS, Leesnitzer MA, Bickett DM, Warner JR, Andersen MW, Badiang JG, Cowan DJ, Gaul MD, Petrov KG, Rabinowitz MH, Wiethe RW, Becherer JD, McDougald DL, Musso DL, Andrews RC, Moss ML. Lambert MH, et al. Among authors: mcdougald dl. Comb Chem High Throughput Screen. 2005 Jun;8(4):327-39. doi: 10.2174/1386207054020840. Comb Chem High Throughput Screen. 2005. PMID: 16101009
Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases.
Conway JG, Andrews RC, Beaudet B, Bickett DM, Boncek V, Brodie TA, Clark RL, Crumrine RC, Leenitzer MA, McDougald DL, Han B, Hedeen K, Lin P, Milla M, Moss M, Pink H, Rabinowitz MH, Tippin T, Scates PW, Selph J, Stimpson SA, Warner J, Becherer JD. Conway JG, et al. Among authors: mcdougald dl. J Pharmacol Exp Ther. 2001 Sep;298(3):900-8. J Pharmacol Exp Ther. 2001. PMID: 11504783
N-hydroxyformamide peptidomimetics as TACE/matrix metalloprotease inhibitors: oral activity via P1' isobutyl substitution.
Musso DL, Andersen MW, Andrews RC, Austin R, Beaudet EJ, Becherer JD, Bubacz DG, Bickett DM, Chan JH, Conway JG, Cowan DJ, Gaul MD, Glennon KC, Hedeen KM, Lambert MH, Leesnitzer MA, McDougald DL, Mitchell JL, Moss ML, Rabinowitz MH, Rizzolio MC, Schaller LT, Stanford JB, Tippin T, Warner JR, Whitesell LG, Wiethe RW. Musso DL, et al. Among authors: mcdougald dl. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2147-51. doi: 10.1016/s0960-894x(01)00377-8. Bioorg Med Chem Lett. 2001. PMID: 11514157