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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2004 1
2005 4
2006 8
2007 1
2008 1
2009 3
2010 17
2011 13
2012 15
2013 13
2014 8
2015 5
2016 7
2017 6
2018 7
2019 4
2020 3
2021 5
2022 10
2023 6
2024 2

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112 results

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Page 1
c-Abl tyrosine kinase down-regulation as target for memory improvement in Alzheimer's disease.
León R, Gutiérrez DA, Pinto C, Morales C, de la Fuente C, Riquelme C, Cortés BI, González-Martin A, Chamorro D, Espinosa N, Fuentealba P, Cancino GI, Zanlungo S, Dulcey AE, Marugan JJ, Álvarez Rojas A. León R, et al. Among authors: marugan jj. Front Aging Neurosci. 2023 Jun 5;15:1180987. doi: 10.3389/fnagi.2023.1180987. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37358955 Free PMC article.
Therapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis.
Kaftanovskaya EM, Ng HH, Soula M, Rivas B, Myhr C, Ho BA, Cervantes BA, Shupe TD, Devarasetty M, Hu X, Xu X, Patnaik S, Wilson KJ, Barnaeva E, Ferrer M, Southall NT, Marugan JJ, Bishop CE, Agoulnik IU, Agoulnik AI. Kaftanovskaya EM, et al. Among authors: marugan jj. FASEB J. 2019 Nov;33(11):12435-12446. doi: 10.1096/fj.201901046R. Epub 2019 Aug 16. FASEB J. 2019. PMID: 31419161 Free PMC article.
The Impact of Assay Design on Medicinal Chemistry: Case Studies.
Born JR, Chenniappan VK, Davis DP, Dahlin JL, Marugan JJ, Patnaik S. Born JR, et al. Among authors: marugan jj. SLAS Discov. 2021 Dec;26(10):1243-1255. doi: 10.1177/24725552211026238. Epub 2021 Jul 5. SLAS Discov. 2021. PMID: 34225522 Free article. Review.
c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration.
Martinez A, Lamaizon CM, Valls C, Llambi F, Leal N, Fitzgerald P, Guy C, Kamiński MM, Inestrosa NC, van Zundert B, Cancino GI, Dulcey AE, Zanlungo S, Marugan JJ, Hetz C, Green DR, Alvarez AR. Martinez A, et al. Among authors: marugan jj. Antioxidants (Basel). 2023 Nov 16;12(11):2007. doi: 10.3390/antiox12112007. Antioxidants (Basel). 2023. PMID: 38001860 Free PMC article.
Discovery of Small Molecule Influenza Virus NS1 Antagonist.
Patnaik S, Basu D, Dehdashti S, Zheng W, Ferrer M, Southall N, Taylor M, Engel DA, Marugan JJ. Patnaik S, et al. Among authors: marugan jj. 2012 Apr 13 [updated 2013 Sep 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Apr 13 [updated 2013 Sep 3]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 24260784 Free Books & Documents. Review.
The pilot phase of the NIH Chemical Genomics Center.
Thomas CJ, Auld DS, Huang R, Huang W, Jadhav A, Johnson RL, Leister W, Maloney DJ, Marugan JJ, Michael S, Simeonov A, Southall N, Xia M, Zheng W, Inglese J, Austin CP. Thomas CJ, et al. Among authors: marugan jj. Curr Top Med Chem. 2009;9(13):1181-93. doi: 10.2174/156802609789753644. Curr Top Med Chem. 2009. PMID: 19807664 Free PMC article. Review.
Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.
Liu L, Tang M, Pragani R, Whitby FG, Zhang YQ, Balakrishnan B, Fang Y, Karavadhi S, Tao D, LeClair CA, Hall MD, Marugan JJ, Boxer M, Shen M, Hill CP, Lai K, Patnaik S. Liu L, et al. Among authors: marugan jj. J Med Chem. 2021 Sep 23;64(18):13551-13571. doi: 10.1021/acs.jmedchem.1c00945. Epub 2021 Sep 7. J Med Chem. 2021. PMID: 34491744 Free PMC article.
Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase.
Rogers S, Patnaik S, Schoenen F, Zheng W, Choi J, Motabar O, Southall N, Westbroek W, Goldin E, Sidransky E, Leister W, Marugan JJ, Aubé J. Rogers S, et al. Among authors: marugan jj. 2012 Mar 27 [updated 2013 Mar 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Mar 27 [updated 2013 Mar 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23762943 Free Books & Documents. Review.
Identification of a G-Protein-Independent Activator of GIRK Channels.
Zhao Y, Ung PM, Zahoránszky-Kőhalmi G, Zakharov AV, Martinez NJ, Simeonov A, Glaaser IW, Rai G, Schlessinger A, Marugan JJ, Slesinger PA. Zhao Y, et al. Among authors: marugan jj. Cell Rep. 2020 Jun 16;31(11):107770. doi: 10.1016/j.celrep.2020.107770. Cell Rep. 2020. PMID: 32553165 Free PMC article.
112 results