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Page 1
An overview of the biology of a long-acting inhaled treprostinil prodrug.
Chapman RW, Corboz MR, Malinin VS, Plaunt AJ, Konicek DM, Li Z, Perkins WR. Chapman RW, et al. Among authors: konicek dm. Pulm Pharmacol Ther. 2020 Dec;65:102002. doi: 10.1016/j.pupt.2021.102002. Epub 2021 Feb 15. Pulm Pharmacol Ther. 2020. PMID: 33596473 Free article. Review.
Characterisation of cough evoked by inhaled treprostinil and treprostinil palmitil.
Chapman RW, Corboz MR, Fernandez C, Sullivan E, Stautberg A, Plaunt AJ, Konicek DM, Malinin V, Li Z, Cipolla D, Perkins W. Chapman RW, et al. Among authors: konicek dm. ERJ Open Res. 2021 Feb 15;7(1):00592-2020. doi: 10.1183/23120541.00592-2020. eCollection 2021 Jan. ERJ Open Res. 2021. PMID: 33614774 Free PMC article.
Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections.
Plaunt AJ, Rose SJ, Kang JY, Chen KJ, LaSala D, Heckler RP, Dorfman A, Smith BT, Chun D, Viramontes V, Macaluso A, Li Z, Zhou Y, Mark L, Basso J, Leifer FG, Corboz MR, Chapman RW, Cipolla D, Perkins WR, Malinin VS, Konicek DM. Plaunt AJ, et al. Among authors: konicek dm. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0031621. doi: 10.1128/AAC.00316-21. Epub 2021 Jun 17. Antimicrob Agents Chemother. 2021. PMID: 33941518 Free PMC article.
Correction for Plaunt et al., "Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections".
Plaunt AJ, Rose SJ, Kang JY, Chen KJ, LaSala D, Heckler RP, Dorfman A, Smith BT, Chun D, Viramontes V, Macaluso A, Li Z, Zhou Y, Mark L, Basso J, Leifer FG, Corboz MR, Chapman RW, Cipolla D, Perkins WR, Malinin VS, Konicek DM. Plaunt AJ, et al. Among authors: konicek dm. Antimicrob Agents Chemother. 2022 Nov 15;66(11):e0125622. doi: 10.1128/aac.01256-22. Epub 2022 Oct 12. Antimicrob Agents Chemother. 2022. PMID: 36222535 Free PMC article. No abstract available.
Inhaled hexadecyl-treprostinil provides pulmonary vasodilator activity at significantly lower plasma concentrations than infused treprostinil.
Chapman RW, Li Z, Corboz MR, Gauani H, Plaunt AJ, Konicek DM, Leifer FG, Laurent CE, Yin H, Salvail D, Dziak C, Perkins WR, Malinin V. Chapman RW, et al. Among authors: konicek dm. Pulm Pharmacol Ther. 2018 Apr;49:104-111. doi: 10.1016/j.pupt.2018.02.002. Epub 2018 Feb 5. Pulm Pharmacol Ther. 2018. PMID: 29421665 Free article.
Preclinical Pharmacology and Pharmacokinetics of Inhaled Hexadecyl-Treprostinil (C16TR), a Pulmonary Vasodilator Prodrug.
Corboz MR, Li Z, Malinin V, Plaunt AJ, Konicek DM, Leifer FG, Chen KJ, Laurent CE, Yin H, Biernat MC, Salvail D, Zhuang J, Xu F, Curran A, Perkins WR, Chapman RW. Corboz MR, et al. Among authors: konicek dm. J Pharmacol Exp Ther. 2017 Dec;363(3):348-357. doi: 10.1124/jpet.117.242099. Epub 2017 Sep 13. J Pharmacol Exp Ther. 2017. PMID: 28904003