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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1993 1
1994 2
1995 1
2006 1
2010 1
2012 1
2013 1
2014 1
2015 2
2016 1
2020 1
2024 0

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12 results

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Page 1
Phase I dose-escalation trial of the oral AKT inhibitor uprosertib in combination with the oral MEK1/MEK2 inhibitor trametinib in patients with solid tumors.
Tolcher AW, Kurzrock R, Valero V, Gonzalez R, Heist RS, Tan AR, Means-Powell J, Werner TL, Becerra C, Wang C, Leonowens C, Kalyana-Sundaram S, Kleha JF, Gauvin J, D'Amelio AM Jr, Ellis C, Ibrahim N, Yan L. Tolcher AW, et al. Among authors: kleha jf. Cancer Chemother Pharmacol. 2020 Apr;85(4):673-683. doi: 10.1007/s00280-020-04038-8. Epub 2020 Feb 15. Cancer Chemother Pharmacol. 2020. PMID: 32062691 Clinical Trial.
First-in-Human Phase I Study of GSK2126458, an Oral Pan-Class I Phosphatidylinositol-3-Kinase Inhibitor, in Patients with Advanced Solid Tumor Malignancies.
Munster P, Aggarwal R, Hong D, Schellens JH, van der Noll R, Specht J, Witteveen PO, Werner TL, Dees EC, Bergsland E, Agarwal N, Kleha JF, Durante M, Adams L, Smith DA, Lampkin TA, Morris SR, Kurzrock R. Munster P, et al. Among authors: kleha jf. Clin Cancer Res. 2016 Apr 15;22(8):1932-9. doi: 10.1158/1078-0432.CCR-15-1665. Epub 2015 Nov 24. Clin Cancer Res. 2016. PMID: 26603258 Clinical Trial.
A randomized, double-blind, placebo-controlled study to evaluate the effect of repeated oral doses of pazopanib on cardiac conduction in patients with solid tumors.
Heath EI, Infante J, Lewis LD, Luu T, Stephenson J, Tan AR, Kasubhai S, LoRusso P, Ma B, Suttle AB, Kleha JF, Ball HA, Dar MM. Heath EI, et al. Among authors: kleha jf. Cancer Chemother Pharmacol. 2013 Mar;71(3):565-73. doi: 10.1007/s00280-012-2030-8. Epub 2013 Jan 24. Cancer Chemother Pharmacol. 2013. PMID: 23344712 Free PMC article. Clinical Trial.
Lack of clinically significant pharmacokinetic interaction between the thrombopoietin receptor agonist eltrombopag and hepatitis C virus protease inhibitors boceprevir and telaprevir.
Wire MB, Fang L, Hussaini A, Kleha JF, Theodore D. Wire MB, et al. Among authors: kleha jf. Antimicrob Agents Chemother. 2014 Nov;58(11):6704-9. doi: 10.1128/AAC.03091-14. Epub 2014 Aug 25. Antimicrob Agents Chemother. 2014. PMID: 25155600 Free PMC article. Clinical Trial.
A comparison of the pharmacokinetics of the anticancer MET inhibitor foretinib free base tablet formulation to bisphosphate salt capsule formulation in patients with solid tumors.
Naing A, Kurzrock R, Adams LM, Kleha JF, Laubscher KH, Bonate PL, Weller S, Fitzgerald C, Xu Y, LoRusso PM. Naing A, et al. Among authors: kleha jf. Invest New Drugs. 2012 Feb;30(1):327-34. doi: 10.1007/s10637-010-9536-x. Epub 2010 Sep 15. Invest New Drugs. 2012. PMID: 20842406 Clinical Trial.
EDRF release from canine coronary artery by lectins.
Kleha JF, Devesly P, Johns A. Kleha JF, et al. Br J Pharmacol. 1993 Dec;110(4):1473-8. doi: 10.1111/j.1476-5381.1993.tb13987.x. Br J Pharmacol. 1993. PMID: 8306089 Free PMC article.
Erratum for Wire et al., Lack of clinically significant pharmacokinetic interaction between the thrombopoietin receptor agonist eltrombopag and hepatitis C virus protease inhibitors boceprevir and telaprevir.
Wire MB, Fang L, Hussaini A, Kleha JF, Theodore D. Wire MB, et al. Among authors: kleha jf. Antimicrob Agents Chemother. 2015 May;59(5):2969. doi: 10.1128/AAC.00567-15. Antimicrob Agents Chemother. 2015. PMID: 25862822 Free PMC article. No abstract available.
12 results