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[(pF)Phe4,Arg14,Lys15]N/OFQ-NH2 (UFP-102), a highly potent and selective agonist of the nociceptin/orphanin FQ receptor.
Carrà G, Rizzi A, Guerrini R, Barnes TA, McDonald J, Hebbes CP, Mela F, Kenigs VA, Marzola G, Rizzi D, Gavioli E, Zucchini S, Regoli D, Morari M, Salvadori S, Rowbotham DJ, Lambert DG, Kapusta DR, Calo' G. Carrà G, et al. Among authors: kenigs va. J Pharmacol Exp Ther. 2005 Mar;312(3):1114-23. doi: 10.1124/jpet.104.077339. Epub 2004 Oct 27. J Pharmacol Exp Ther. 2005. PMID: 15509719
Pharmacodynamic characterization of ZP120 (Ac-RYYRWKKKKKKK-NH2), a novel, functionally selective nociceptin/orphanin FQ peptide receptor partial agonist with sodium-potassium-sparing aquaretic activity.
Kapusta DR, Thorkildsen C, Kenigs VA, Meier E, Vinge MM, Quist C, Petersen JS. Kapusta DR, et al. Among authors: kenigs va. J Pharmacol Exp Ther. 2005 Aug;314(2):652-60. doi: 10.1124/jpet.105.083436. Epub 2005 Apr 26. J Pharmacol Exp Ther. 2005. PMID: 15855355
Differential cardiovascular and renal responses produced by microinjection of the {kappa}-opioid U-50488H [(trans-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-benzene-acetamide) methane sulfonate] into subregions of the paraventricular nucleus.
Gottlieb HB, Varner KJ, Kenigs VA, Cabral AM, Kapusta DR. Gottlieb HB, et al. Among authors: kenigs va. J Pharmacol Exp Ther. 2005 Feb;312(2):678-85. doi: 10.1124/jpet.104.076828. Epub 2004 Sep 20. J Pharmacol Exp Ther. 2005. PMID: 15381735