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Naturally occurring variants of human CBR3 alter anthracycline in vitro metabolism.
J Pharmacol Exp Ther. 2010 Mar;332(3):755-63. doi: 10.1124/jpet.109.160614. Epub 2009 Dec 9.
J Pharmacol Exp Ther. 2010.
PMID: 20007405
Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin.
Bains OS, Karkling MJ, Grigliatti TA, Reid RE, Riggs KW.
Bains OS, et al. Among authors: karkling mj.
Drug Metab Dispos. 2009 May;37(5):1107-14. doi: 10.1124/dmd.108.024711. Epub 2009 Feb 9.
Drug Metab Dispos. 2009.
PMID: 19204081
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