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A novel potent radical scavenger, 8-(4-fluorophenyl)-2-((2E)-3-phenyl-2-propenoyl)-1,2,3,4-tetrahydropyrazolo[5,1-c] [1,2,4]triazine (FR210575), prevents neuronal cell death in cultured primary neurons and attenuates brain injury after focal ischemia in rats.
Iwashita A, Maemoto T, Nakada H, Shima I, Matsuoka N, Hisajima H. Iwashita A, et al. Among authors: hisajima h. J Pharmacol Exp Ther. 2003 Dec;307(3):961-8. doi: 10.1124/jpet.103.056572. Epub 2003 Oct 8. J Pharmacol Exp Ther. 2003. PMID: 14534357
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