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2014 | 1 |
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Biased ligands: pathway validation for novel GPCR therapeutics.
Curr Opin Pharmacol. 2014 Jun;16:108-15. doi: 10.1016/j.coph.2014.04.002. Epub 2014 May 14.
Curr Opin Pharmacol. 2014.
PMID: 24834870
Review.
Quantifying ligand bias at seven-transmembrane receptors.
Rajagopal S, Ahn S, Rominger DH, Gowen-MacDonald W, Lam CM, Dewire SM, Violin JD, Lefkowitz RJ.
Rajagopal S, et al. Among authors: gowen macdonald w.
Mol Pharmacol. 2011 Sep;80(3):367-77. doi: 10.1124/mol.111.072801. Epub 2011 May 24.
Mol Pharmacol. 2011.
PMID: 21610196
Free PMC article.
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TRV0109101, a G Protein-Biased Agonist of the µ-Opioid Receptor, Does Not Promote Opioid-Induced Mechanical Allodynia following Chronic Administration.
Koblish M, Carr R 3rd, Siuda ER, Rominger DH, Gowen-MacDonald W, Cowan CL, Crombie AL, Violin JD, Lark MW.
Koblish M, et al. Among authors: gowen macdonald w.
J Pharmacol Exp Ther. 2017 Aug;362(2):254-262. doi: 10.1124/jpet.117.241117. Epub 2017 May 22.
J Pharmacol Exp Ther. 2017.
PMID: 28533287
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