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Did you mean fleagle j[au] (90 results)?
CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection.
Foreman TW, Nelson CE, Kauffman KD, Lora NE, Vinhaes CL, Dorosky DE, Sakai S, Gomez F, Fleegle JD, Parham M, Perera SR, Lindestam Arlehamn CS, Sette A; Tuberculosis Imaging Program; Brenchley JM, Queiroz ATL, Andrade BB, Kabat J, Via LE, Barber DL. Foreman TW, et al. Among authors: fleegle jd. Cell Rep. 2022 May 31;39(9):110896. doi: 10.1016/j.celrep.2022.110896. Cell Rep. 2022. PMID: 35649361 Free article.
Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates.
Sakai S, Lora NE, Kauffman KD, Dorosky DE, Oh S, Namasivayam S, Gomez F, Fleegle JD; Tuberculosis Imaging Program; Arlehamn CSL, Sette A, Sher A, Freeman GJ, Via LE, Barry Iii CE, Barber DL. Sakai S, et al. Among authors: fleegle jd. Mucosal Immunol. 2021 Sep;14(5):1055-1066. doi: 10.1038/s41385-021-00425-3. Epub 2021 Jun 22. Mucosal Immunol. 2021. PMID: 34158594 Free PMC article.
Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities.
Boshoff HIM, Young K, Ahn YM, Yadav VD, Crowley BM, Yang L, Su J, Oh S, Arora K, Andrews J, Manikkam M, Sutphin M, Smith AJ, Weiner DM, Piazza MK, Fleegle JD, Gomez F, Dayao EK, Prideaux B, Zimmerman M, Kaya F, Sarathy J, Tan VY, Via LE, Tschirret-Guth R, Lenaerts AJ, Robertson GT, Dartois V, Olsen DB, Barry CE 3rd. Boshoff HIM, et al. Among authors: fleegle jd. ACS Infect Dis. 2024 Apr 6. doi: 10.1021/acsinfecdis.4c00025. Online ahead of print. ACS Infect Dis. 2024. PMID: 38581700
IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques.
Nelson CE, Foreman TW, Kauffman KD, Sakai S, Gould ST, Fleegle JD, Gomez F; NIAID/DIR Tuberculosis Imaging Program; Le Nouën C, Liu X, Burdette TL, Garza NL, Lafont BAP, Brooks K, Arlehamn CSL, Weiskopf D, Sette A, Hickman HD, Buchholz UJ, Johnson RF, Brenchley JM, Via LE, Barber DL. Nelson CE, et al. Among authors: fleegle jd. bioRxiv [Preprint]. 2022 Sep 15:2022.09.13.507852. doi: 10.1101/2022.09.13.507852. bioRxiv. 2022. PMID: 36172119 Free PMC article. Preprint.
Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits.
Datta M, Via LE, Dartois V, Weiner DM, Zimmerman M, Kaya F, Walker AM, Fleegle JD, Raplee ID, McNinch C, Zarodniuk M, Kamoun WS, Yue C, Kumar AS, Subudhi S, Xu L, Barry CE 3rd, Jain RK. Datta M, et al. Among authors: fleegle jd. Proc Natl Acad Sci U S A. 2024 Apr 2;121(14):e2321336121. doi: 10.1073/pnas.2321336121. Epub 2024 Mar 26. Proc Natl Acad Sci U S A. 2024. PMID: 38530888 Free PMC article.
Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease.
Hirsh AJ, Zhang J, Zamurs A, Fleegle J, Thelin WR, Caldwell RA, Sabater JR, Abraham WM, Donowitz M, Cha B, Johnson KB, St George JA, Johnson MR, Boucher RC. Hirsh AJ, et al. Among authors: fleegle j. J Pharmacol Exp Ther. 2008 Apr;325(1):77-88. doi: 10.1124/jpet.107.130443. Epub 2008 Jan 24. J Pharmacol Exp Ther. 2008. PMID: 18218832