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Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice.
J Pharmacol Exp Ther. 2006 Jul;318(1):173-85. doi: 10.1124/jpet.106.102046. Epub 2006 Apr 11.
J Pharmacol Exp Ther. 2006.
PMID: 16608916
A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity.
Galici R, Echemendia NG, Rodriguez AL, Conn PJ.
Galici R, et al. Among authors: echemendia ng.
J Pharmacol Exp Ther. 2005 Dec;315(3):1181-7. doi: 10.1124/jpet.105.091074. Epub 2005 Aug 25.
J Pharmacol Exp Ther. 2005.
PMID: 16123306
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