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A single administration of recombinant human interleukin-12 is associated with increased expression levels of interferon-gamma and signal transducer and activator of transcription in healthy subjects.
Trudeau C, Cotreau MM, Stonis L, Dykstra KH, Oestreicher JL, Strahs A, Dorner AJ, Van Cleave VH, Trepicchio WL, Schwertschlag US. Trudeau C, et al. Among authors: dykstra kh. J Clin Pharmacol. 2005 Jun;45(6):649-58. doi: 10.1177/0091270005276116. J Clin Pharmacol. 2005. PMID: 15901746
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