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An orally active inhibitor of renin.
Pals DT, Thaisrivongs S, Lawson JA, Kati WM, Turner SR, DeGraaf GL, Harris DW, Johnson GA. Pals DT, et al. Among authors: degraaf gl. Hypertension. 1986 Dec;8(12):1105-12. doi: 10.1161/01.hyp.8.12.1105. Hypertension. 1986. PMID: 3539793
Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin infused rat model and in conscious sodium-depleted monkeys.
Thaisrivongs S, Pals DT, DuCharme DW, Turner SR, DeGraaf GL, Lawson JA, Couch SJ, Williams MV. Thaisrivongs S, et al. Among authors: degraaf gl. J Med Chem. 1991 Feb;34(2):633-42. doi: 10.1021/jm00106a026. J Med Chem. 1991. PMID: 1995887
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