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Page 1
Senicapoc: Repurposing a Drug to Target Microglia KCa3.1 in Stroke.
Staal RGW, Weinstein JR, Nattini M, Cajina M, Chandresana G, Möller T. Staal RGW, et al. Among authors: cajina m. Neurochem Res. 2017 Sep;42(9):2639-2645. doi: 10.1007/s11064-017-2223-y. Epub 2017 Mar 31. Neurochem Res. 2017. PMID: 28364331 Free PMC article. Review.
Synthesis and Characterization of the Novel Rodent-Active and CNS-Penetrant P2X7 Receptor Antagonist Lu AF27139.
Hopper AT, Juhl M, Hornberg J, Badolo L, Kilburn JP, Thougaard A, Smagin G, Song D, Calice L, Menon V, Dale E, Zhang H, Cajina M, Nattini ME, Gandhi A, Grenon M, Jones K, Khayrullina T, Chandrasena G, Thomsen C, Zorn SH, Brodbeck R, Poda SB, Staal R, Möller T. Hopper AT, et al. Among authors: cajina m. J Med Chem. 2021 Apr 22;64(8):4891-4902. doi: 10.1021/acs.jmedchem.0c02249. Epub 2021 Apr 6. J Med Chem. 2021. PMID: 33822617
P2X7 receptor-mediated release of microglial prostanoids and miRNAs correlates with reversal of neuropathic hypersensitivity in rats.
Staal R, Khayrullina T, Christensen R, Hestehave S, Zhou H, Cajina M, Nattini ME, Gandhi A, Fallon SM, Schmidt M, Zorn SH, Brodbeck RM, Chandrasena G, Segerdahl M, Breysse N, Hopper AT, Möller T, Munro G. Staal R, et al. Among authors: cajina m. Eur J Pain. 2022 Jul;26(6):1304-1321. doi: 10.1002/ejp.1951. Epub 2022 Apr 22. Eur J Pain. 2022. PMID: 35388574
Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept.
Jacobsen JPR, Oh A, Bangle R, Roberts WL, Royer EL, Modesto N, Windermere SA, Yi Z, Vernon R, Cajina M, Urs NM, Snyder JC, Nicholls PJ, Sachs BD, Caron MG. Jacobsen JPR, et al. Among authors: cajina m. Neuropsychopharmacology. 2019 Nov;44(12):2082-2090. doi: 10.1038/s41386-019-0400-1. Epub 2019 Apr 29. Neuropsychopharmacology. 2019. PMID: 31035282 Free PMC article.
Inhibition of P2X7 receptors by Lu AF27139 diminishes colonic hypersensitivity and CNS prostanoid levels in a rat model of visceral pain.
Staal RGW, Gandhi A, Zhou H, Cajina M, Jacobsen AM, Hestehave S, Hopper A, Poda S, Chandresana G, Zorn SH, Campbell B, Segerdahl M, Mӧller T, Munro G. Staal RGW, et al. Among authors: cajina m. Purinergic Signal. 2022 Dec;18(4):499-514. doi: 10.1007/s11302-022-09892-0. Epub 2022 Aug 24. Purinergic Signal. 2022. PMID: 36001278 Free PMC article.
The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse.
Jacobsen JP, Plenge P, Sachs BD, Pehrson AL, Cajina M, Du Y, Roberts W, Rudder ML, Dalvi P, Robinson TJ, O'Neill SP, Khoo KS, Morillo CS, Zhang X, Caron MG. Jacobsen JP, et al. Among authors: cajina m. Psychopharmacology (Berl). 2014 Dec;231(23):4527-40. doi: 10.1007/s00213-014-3595-1. Epub 2014 May 9. Psychopharmacology (Berl). 2014. PMID: 24810106 Free PMC article.
15 results