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Year Number of Results
1960 1
1963 1
1967 1
1986 1
1990 1
1992 1
2009 1
2015 1
2017 1
2018 7
2019 6
2020 3
2021 2
2022 3
2023 4
2024 3

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35 results

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Page 1
Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.
Abskharon R, Pan H, Sawaya MR, Seidler PM, Olivares EJ, Chen Y, Murray KA, Zhang J, Lantz C, Bentzel M, Boyer DR, Cascio D, Nguyen BA, Hou K, Cheng X, Pardon E, Williams CK, Nana AL, Vinters HV, Spina S, Grinberg LT, Seeley WW, Steyaert J, Glabe CG, Ogorzalek Loo RR, Loo JA, Eisenberg DS. Abskharon R, et al. Among authors: boyer dr. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2300258120. doi: 10.1073/pnas.2300258120. Epub 2023 Oct 6. Proc Natl Acad Sci U S A. 2023. PMID: 37801475 Free PMC article.
Structure-based inhibitors of tau aggregation.
Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS. Seidler PM, et al. Among authors: boyer dr. Nat Chem. 2018 Feb;10(2):170-176. doi: 10.1038/nchem.2889. Epub 2017 Nov 20. Nat Chem. 2018. PMID: 29359764 Free PMC article.
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils.
Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Among authors: boyer dr. Nat Commun. 2023 Apr 25;14(1):2379. doi: 10.1038/s41467-023-37865-3. Nat Commun. 2023. PMID: 37185252 Free PMC article.
Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2.
Tayeb-Fligelman E, Cheng X, Tai C, Bowler JT, Griner S, Sawaya MR, Seidler PM, Jiang YX, Lu J, Rosenberg GM, Salwinski L, Abskharon R, Zee CT, Hou K, Li Y, Boyer DR, Murray KA, Falcon G, Anderson DH, Cascio D, Saelices L, Damoiseaux R, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Among authors: boyer dr. bioRxiv [Preprint]. 2021 Mar 18:2021.03.05.434000. doi: 10.1101/2021.03.05.434000. bioRxiv. 2021. PMID: 33688654 Free PMC article. Preprint.
Cryo-EM structures of four polymorphic TDP-43 amyloid cores.
Cao Q, Boyer DR, Sawaya MR, Ge P, Eisenberg DS. Cao Q, et al. Among authors: boyer dr. Nat Struct Mol Biol. 2019 Jul;26(7):619-627. doi: 10.1038/s41594-019-0248-4. Epub 2019 Jun 24. Nat Struct Mol Biol. 2019. PMID: 31235914 Free PMC article.
Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp.
Gallagher-Jones M, Glynn C, Boyer DR, Martynowycz MW, Hernandez E, Miao J, Zee CT, Novikova IV, Goldschmidt L, McFarlane HT, Helguera GF, Evans JE, Sawaya MR, Cascio D, Eisenberg DS, Gonen T, Rodriguez JA. Gallagher-Jones M, et al. Among authors: boyer dr. Nat Struct Mol Biol. 2018 Feb;25(2):131-134. doi: 10.1038/s41594-017-0018-0. Epub 2018 Jan 15. Nat Struct Mol Biol. 2018. PMID: 29335561 Free PMC article.
35 results