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Phosphodiesterase inhibitors.
Boswell-Smith V, Spina D, Page CP. Boswell-Smith V, et al. Br J Pharmacol. 2006 Jan;147 Suppl 1(Suppl 1):S252-7. doi: 10.1038/sj.bjp.0706495. Br J Pharmacol. 2006. PMID: 16402111 Free PMC article. Review.
Are phosphodiesterase 4 inhibitors just more theophylline?
Boswell-Smith V, Cazzola M, Page CP. Boswell-Smith V, et al. J Allergy Clin Immunol. 2006 Jun;117(6):1237-43. doi: 10.1016/j.jaci.2006.02.045. Epub 2006 May 3. J Allergy Clin Immunol. 2006. PMID: 16750981 Review.
The pharmacology of two novel long-acting phosphodiesterase 3/4 inhibitors, RPL554 [9,10-dimethoxy-2(2,4,6-trimethylphenylimino)-3-(n-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one] and RPL565 [6,7-dihydro-2-(2,6-diisopropylphenoxy)-9,10-dimethoxy-4H-pyrimido[6,1-a]isoquinolin-4-one].
Boswell-Smith V, Spina D, Oxford AW, Comer MB, Seeds EA, Page CP. Boswell-Smith V, et al. J Pharmacol Exp Ther. 2006 Aug;318(2):840-8. doi: 10.1124/jpet.105.099192. Epub 2006 May 8. J Pharmacol Exp Ther. 2006. PMID: 16682455
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives.
Costanzo MJ, Yabut SC, Zhang HC, White KB, de Garavilla L, Wang Y, Minor LK, Tounge BA, Barnakov AN, Lewandowski F, Milligan C, Spurlino JC, Abraham WM, Boswell-Smith V, Page CP, Maryanoff BE. Costanzo MJ, et al. Among authors: boswell smith v. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2114-21. doi: 10.1016/j.bmcl.2008.01.093. Epub 2008 Jan 30. Bioorg Med Chem Lett. 2008. PMID: 18272363