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Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole.
Clin Pharmacol Ther. 2007 Sep;82(3):265-74. doi: 10.1038/sj.clpt.6100138. Epub 2007 Mar 7.
Clin Pharmacol Ther. 2007.
PMID: 17344806
MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms.
Blievernicht JK, Schaeffeler E, Klein K, Eichelbaum M, Schwab M, Zanger UM.
Blievernicht JK, et al.
Clin Chem. 2007 Jan;53(1):24-33. doi: 10.1373/clinchem.2006.074856. Epub 2006 Nov 2.
Clin Chem. 2007.
PMID: 17082249
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Cytochrome P450 2B6 activity as measured by bupropion hydroxylation: effect of induction by rifampin and ethnicity.
Loboz KK, Gross AS, Williams KM, Liauw WS, Day RO, Blievernicht JK, Zanger UM, McLachlan AJ.
Loboz KK, et al. Among authors: blievernicht jk.
Clin Pharmacol Ther. 2006 Jul;80(1):75-84. doi: 10.1016/j.clpt.2006.03.010.
Clin Pharmacol Ther. 2006.
PMID: 16815319
Clinical Trial.
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Aberrant splicing caused by single nucleotide polymorphism c.516G>T [Q172H], a marker of CYP2B6*6, is responsible for decreased expression and activity of CYP2B6 in liver.
Hofmann MH, Blievernicht JK, Klein K, Saussele T, Schaeffeler E, Schwab M, Zanger UM.
Hofmann MH, et al. Among authors: blievernicht jk.
J Pharmacol Exp Ther. 2008 Apr;325(1):284-92. doi: 10.1124/jpet.107.133306. Epub 2008 Jan 2.
J Pharmacol Exp Ther. 2008.
PMID: 18171905
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