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Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor.
Andrade-Gordon P, Maryanoff BE, Derian CK, Zhang HC, Addo MF, Darrow AL, Eckardt AJ, Hoekstra WJ, McComsey DF, Oksenberg D, Reynolds EE, Santulli RJ, Scarborough RM, Smith CE, White KB. Andrade-Gordon P, et al. Among authors: addo mf. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12257-62. doi: 10.1073/pnas.96.22.12257. Proc Natl Acad Sci U S A. 1999. PMID: 10535908 Free PMC article.
Discovery and optimization of a novel series of thrombin receptor (par-1) antagonists: potent, selective peptide mimetics based on indole and indazole templates.
Zhang HC, Derian CK, Andrade-Gordon P, Hoekstra WJ, McComsey DF, White KB, Poulter BL, Addo MF, Cheung WM, Damiano BP, Oksenberg D, Reynolds EE, Pandey A, Scarborough RM, Maryanoff BE. Zhang HC, et al. Among authors: addo mf. J Med Chem. 2001 Mar 29;44(7):1021-4. doi: 10.1021/jm000506s. J Med Chem. 2001. PMID: 11297447 No abstract available.
Administration of a potent antagonist of protease-activated receptor-1 (PAR-1) attenuates vascular restenosis following balloon angioplasty in rats.
Andrade-Gordon P, Derian CK, Maryanoff BE, Zhang HC, Addo MF, Cheung Wm, Damiano BP, D'Andrea MR, Darrow AL, de Garavilla L, Eckardt AJ, Giardino EC, Haertlein BJ, McComsey DF. Andrade-Gordon P, et al. Among authors: addo mf. J Pharmacol Exp Ther. 2001 Jul;298(1):34-42. J Pharmacol Exp Ther. 2001. PMID: 11408522
18 results