Abstract
The enterohepatic circulation of bile acids is maintained by a series of membrane transport proteins. Recent studies of the cloned sodium bile acid cotransporters have provided new insights into their tissue expression, regulation, and their relationship to cholesterol homeostasis and human diseases such as primary bile acid malabsorption.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Bile Acids and Salts / metabolism*
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Biological Transport, Active
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Carrier Proteins / genetics
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Carrier Proteins / metabolism
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Cholesterol / metabolism
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Enterohepatic Circulation
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Homeostasis
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Humans
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Intestinal Mucosa / metabolism
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Liver / metabolism
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Malabsorption Syndromes / genetics
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Malabsorption Syndromes / metabolism
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Organic Anion Transporters, Sodium-Dependent*
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Symporters*
Substances
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Bile Acids and Salts
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Carrier Proteins
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Organic Anion Transporters, Sodium-Dependent
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Symporters
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sodium-bile acid cotransporter
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Cholesterol