S 18886, a new thromboxane (TP)-receptor antagonist is the active isomer of S 18204 in all species, except in the guinea-pig

Adv Exp Med Biol. 1997:433:173-6. doi: 10.1007/978-1-4899-1810-9_35.
No abstract available

MeSH terms

  • 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid / pharmacology
  • Animals
  • Bronchoconstriction / drug effects
  • Dogs
  • Guinea Pigs
  • Humans
  • Muscle Contraction / drug effects*
  • Muscle, Smooth / drug effects
  • Muscle, Smooth / physiology
  • Naphthalenes
  • Platelet Aggregation / drug effects*
  • Propionates
  • Rabbits
  • Receptors, Thromboxane / antagonists & inhibitors*
  • Species Specificity
  • Stereoisomerism
  • Tetrahydronaphthalenes / chemistry
  • Tetrahydronaphthalenes / pharmacology*
  • Trachea / physiology

Substances

  • Naphthalenes
  • Propionates
  • Receptors, Thromboxane
  • Tetrahydronaphthalenes
  • 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
  • terutroban