Abstract
We tested the influence of urethane, chloral hydrate and a mixture of ketamine/xylazine on Fos protein expression in autonomic brain regions related to blood pressure. We conclude that ketamine/xylazine is a suitable anesthetic to be used in studies looking at c-fos expression in neural circuits serving cardiovascular regulation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anesthetics / pharmacology*
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Anesthetics, General / pharmacology
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Animals
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Autonomic Nervous System / drug effects
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Autonomic Nervous System / metabolism*
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Brain / anatomy & histology
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Brain / drug effects
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Brain / physiology*
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Chloral Hydrate / pharmacology
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Hemodynamics / drug effects
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Hemodynamics / physiology*
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Immunohistochemistry
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Ketamine / pharmacology
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Male
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Proto-Oncogene Proteins c-fos / biosynthesis*
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Rats
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Rats, Sprague-Dawley
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Urethane / pharmacology
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Xylazine / pharmacology
Substances
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Anesthetics
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Anesthetics, General
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Proto-Oncogene Proteins c-fos
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Xylazine
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Urethane
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Chloral Hydrate
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Ketamine