The role of excitotoxicity in organophosphorous nerve agents central poisoning

Trends Pharmacol Sci. 1997 Jun;18(6):183-5. doi: 10.1016/s0165-6147(97)89540-5.
No abstract available

Publication types

  • Review

MeSH terms

  • Brain / cytology
  • Brain / drug effects
  • Brain / pathology
  • Chemical Warfare Agents / poisoning*
  • Cholinesterase Inhibitors / poisoning*
  • Convulsants / poisoning*
  • Excitatory Amino Acid Antagonists / therapeutic use
  • Humans
  • Neurons / cytology
  • Neurons / drug effects
  • Neurons / pathology
  • Organophosphate Poisoning*
  • Organophosphates
  • Organothiophosphorus Compounds / poisoning
  • Receptors, N-Methyl-D-Aspartate / drug effects
  • Receptors, N-Methyl-D-Aspartate / metabolism
  • Sarin / poisoning
  • Seizures / chemically induced*
  • Seizures / drug therapy
  • Seizures / physiopathology
  • Soman / poisoning
  • Synaptic Transmission / drug effects

Substances

  • Chemical Warfare Agents
  • Cholinesterase Inhibitors
  • Convulsants
  • Excitatory Amino Acid Antagonists
  • Organophosphates
  • Organothiophosphorus Compounds
  • Receptors, N-Methyl-D-Aspartate
  • Soman
  • VX
  • Sarin
  • tabun