Abstract
Abnormal-delta8-tetrahydrocannabinol (ABN-delta8-THC) failed to elicit central nervous system and cardiovascular effects in laboratory animals. Abnormal-cannabidiol (ABN-CBD) was also devoid of overt behavioral effects but produced marked hypotension with only slight bradycardia in anesthesized dogs.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Animals
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Behavior, Animal / drug effects*
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Blood Pressure / drug effects*
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Cannabidiol / analogs & derivatives
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Cannabinoids / pharmacology*
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Dogs
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Dronabinol / analogs & derivatives
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Female
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Heart Rate / drug effects*
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Male
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Mice
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Motor Activity / drug effects*
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Structure-Activity Relationship
Substances
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Cannabinoids
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Cannabidiol
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Dronabinol