Pharmacological modulation of voltage-gated Na+ channels: a rational and effective strategy against ischemic brain damage

Pharmacol Rev. 1996 Mar;48(1):21-67.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Brain / cytology
  • Brain / drug effects
  • Brain / metabolism
  • Brain Ischemia / drug therapy*
  • Brain Ischemia / physiopathology
  • Brain Ischemia / prevention & control
  • Calcium Channels / drug effects
  • Central Nervous System / drug effects
  • Central Nervous System / metabolism
  • Down-Regulation
  • Energy Metabolism
  • Homeostasis
  • Humans
  • Neurons / cytology
  • Neurons / drug effects
  • Neurons / metabolism
  • Neuroprotective Agents / administration & dosage
  • Neuroprotective Agents / pharmacology
  • Neuroprotective Agents / therapeutic use*
  • Phosphorylation
  • Saxitoxin / pharmacology
  • Saxitoxin / therapeutic use
  • Sodium / metabolism
  • Sodium Channels / drug effects*
  • Sodium Channels / metabolism
  • Tetrodotoxin / pharmacology
  • Tetrodotoxin / therapeutic use

Substances

  • Calcium Channels
  • Neuroprotective Agents
  • Sodium Channels
  • Saxitoxin
  • Tetrodotoxin
  • Sodium