A novel sequence polymorphism in the promoter region of the human B2-bradykinin receptor gene

A Braun; E Maier; S Kammerer; B Müller; A A Roscher

doi:10.1007/BF02281884

A novel sequence polymorphism in the promoter region of the human B2-bradykinin receptor gene

Hum Genet. 1996 May;97(5):688-9. doi: 10.1007/BF02281884.

Authors

A Braun¹, E Maier, S Kammerer, B Müller, A A Roscher

Affiliation

¹ Children's Hospital, Department of Clinical Chemistry and Biochemistry, University of Munich, Germany.

PMID: 8655154
DOI: 10.1007/BF02281884

Abstract

The distribution of a nucleotide polymorphism in the core promoter of the human B2-bradykinin receptor gene was examined in the population of southern Germany. The allelic frequencies were 0.595 for C allele and 0.405 for the T allele. The allele frequencies were in Hardy-Weinberg equilibrium. This new marker provides a valuable tool to assess the risk for putative bradykinin-associated disorders with genetic determinism.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Base Sequence
DNA / chemistry
DNA / isolation & purification
DNA Primers
Electrophoresis, Polyacrylamide Gel
Gene Frequency
Genetic Markers
Germany
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic*
Promoter Regions, Genetic*
Receptor, Bradykinin B2
Receptors, Bradykinin / genetics*

Substances

DNA Primers
Genetic Markers
Receptor, Bradykinin B2
Receptors, Bradykinin
DNA

Associated data

GENBANK/X91663
GENBANK/X91664