OKT4A (a murine IgG2a anti-CD4 monoclonal antibody) in human organ transplantation: pharmacokinetics and peripheral pharmacodynamics

Transplant Proc. 1993 Feb;25(1 Pt 1):800-1.

Authors

K R Henell¹, J M Cheever, J A Kimball, W C Lye, M Y Munar, J Misiti, C Vitow, D J Norman

Affiliation

¹ Laboratory of Immunogenetics and Transplantation, Oregon Health Sciences University, Portland 97201.

PMID: 8438489

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Monoclonal / blood*
Antibodies, Monoclonal / pharmacology
CD4 Antigens / metabolism
Dose-Response Relationship, Drug
Drug Therapy, Combination
Enzyme-Linked Immunosorbent Assay
Heart Transplantation / immunology*
Heart Transplantation / physiology
Humans
Immunoglobulin G / blood*
Immunoglobulin G / pharmacology
Immunosuppressive Agents / pharmacokinetics*
Immunosuppressive Agents / pharmacology
Kidney Transplantation / immunology*
Kidney Transplantation / physiology
Lymphocytes / immunology*

Substances

Antibodies, Monoclonal
CD4 Antigens
Immunoglobulin G
Immunosuppressive Agents
OKT4A monoclonal antibody