The isolation of rat intestinal microsomes with stable cytochrome P-450 and their metabolism of benzo(alpha) pyrene

Arch Biochem Biophys. 1976 Nov;177(1):105-16. doi: 10.1016/0003-9861(76)90420-3.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Benzopyrenes / metabolism*
  • Cell Fractionation
  • Cytochrome P-450 Enzyme System / metabolism*
  • Drug Stability
  • Fasting
  • Intestine, Small / metabolism*
  • Kinetics
  • Male
  • Methylcholanthrene / pharmacology
  • Microsomes / drug effects
  • Microsomes / metabolism*
  • Microsomes / ultrastructure
  • NADPH-Ferrihemoprotein Reductase / metabolism
  • Oxygenases / metabolism
  • Phenobarbital / pharmacology
  • Rats

Substances

  • Benzopyrenes
  • Methylcholanthrene
  • Cytochrome P-450 Enzyme System
  • Oxygenases
  • NADPH-Ferrihemoprotein Reductase
  • Phenobarbital