Cardioselective anti-ischemic ATP-sensitive potassium channel openers

J Med Chem. 1993 Nov 26;36(24):3971-4. doi: 10.1021/jm00076a027.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Adenosine Triphosphate / pharmacology*
  • Animals
  • Aorta / drug effects
  • Aorta / physiology
  • Benzopyrans / chemistry*
  • Benzopyrans / pharmacokinetics
  • Benzopyrans / pharmacology
  • Benzopyrans / therapeutic use
  • Biological Availability
  • Cocaine / analogs & derivatives*
  • Cocaine / chemical synthesis
  • Cocaine / metabolism
  • Cocaine / pharmacology
  • Cromakalim
  • Guanidines / chemistry*
  • Guanidines / pharmacokinetics
  • Guanidines / therapeutic use
  • Ion Channel Gating / drug effects*
  • Molecular Structure
  • Myocardial Ischemia / drug therapy*
  • Potassium Channels / drug effects
  • Potassium Channels / physiology*
  • Pyrroles / pharmacology
  • Rats
  • Structure-Activity Relationship
  • Vasodilation / drug effects

Substances

  • Benzopyrans
  • Guanidines
  • Potassium Channels
  • Pyrroles
  • Cromakalim
  • methyl 3-benzoyloxy-7-methoxy-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylate
  • Adenosine Triphosphate
  • BMS 180448
  • Cocaine