The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential

J Med Chem. 1994 Nov 25;37(24):4053-67. doi: 10.1021/jm00050a001.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Anxiety Agents / pharmacology
  • Antipsychotic Agents / pharmacology
  • Binding Sites
  • Cognition / drug effects
  • Glycine / antagonists & inhibitors*
  • Glycine / metabolism
  • Humans
  • Kynurenic Acid / pharmacology
  • Neuroprotective Agents / pharmacology
  • Pyrrolidinones / pharmacology
  • Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors*
  • Receptors, N-Methyl-D-Aspartate / physiology
  • Structure-Activity Relationship

Substances

  • Anti-Anxiety Agents
  • Antipsychotic Agents
  • Neuroprotective Agents
  • Pyrrolidinones
  • Receptors, N-Methyl-D-Aspartate
  • 1-hydroxy-3-amino-2-pyrrolidone
  • Kynurenic Acid
  • Glycine