Abstract
Two elderly patients with Parkinson's disease were treated with nicotine gum and patch. Reliable changes in symptomatology were noted, using a single-subject, placebo-control reversal design. Improvement was associated with active nicotine dosing and involved diminished tremor and disorganized thinking in one patient and diminished bradykinesia and increased energy in the other.
Publication types
-
Case Reports
-
Clinical Trial
-
Controlled Clinical Trial
MeSH terms
-
Administration, Cutaneous
-
Aged
-
Chewing Gum
-
Confusion / drug therapy
-
Confusion / etiology
-
Female
-
Humans
-
Male
-
Middle Aged
-
Muscle Rigidity / drug therapy
-
Muscle Rigidity / etiology
-
Nicotine / administration & dosage
-
Nicotine / therapeutic use*
-
Parkinson Disease / drug therapy*
-
Parkinson Disease / physiopathology
-
Parkinson Disease / psychology
-
Sleep Wake Disorders / drug therapy
-
Sleep Wake Disorders / etiology
-
Tremor / drug therapy
-
Tremor / etiology