Abstract
This article reviews published evidence describing the enzymatic and nonenzymatic formation and the routes of metabolism of the hepoxilins. Also treated are the major approaches used for the chemical synthesis of these compounds and for some of their analogs.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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8,11,14-Eicosatrienoic Acid / analogs & derivatives
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8,11,14-Eicosatrienoic Acid / chemical synthesis
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8,11,14-Eicosatrienoic Acid / metabolism
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Animals
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Drug Stability
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Leukotrienes / chemical synthesis
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Leukotrienes / metabolism*
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Molecular Structure
Substances
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Leukotrienes
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12-HPETE
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10-hydroxy-11,12-epoxyeicosa-5,8,14-trienoic acid
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8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid
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8,11,14-Eicosatrienoic Acid