Metabolic modification by insulin enhances methotrexate cytotoxicity in MCF-7 human breast cancer cells

Eur J Cancer Clin Oncol. 1981 Nov;17(11):1223-8.
No abstract available

MeSH terms

  • Breast Neoplasms / metabolism*
  • Cell Line
  • Cell Survival / drug effects*
  • Cells, Cultured
  • Dose-Response Relationship, Drug
  • Drug Synergism
  • Humans
  • Insulin / pharmacology*
  • Methotrexate / toxicity*
  • Neoplasms, Experimental / metabolism

Substances

  • Insulin
  • Methotrexate