Adverse reactions to trimethoprim-sulfamethoxazole in hospitalized patients

Rev Infect Dis. 1982 Mar-Apr;4(2):426-8. doi: 10.1093/clinids/4.2.426.

Abstract

Of 1,121 hospitalized recipients of trimethoprim-sulfamethoxazole, 91 (8%) experienced reactions that were attributed to this drug. The most common adverse effects were gastrointestinal upset (3.9%) and skin reactions (3.3%). Serious toxicity attributable to the drug was rare.

MeSH terms

  • Adult
  • Aged
  • Drug Combinations / adverse effects
  • Drug Hypersensitivity
  • Female
  • Gastrointestinal Diseases / chemically induced
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Sulfamethoxazole / adverse effects*
  • Thrombocytopenia / chemically induced
  • Trimethoprim / adverse effects*
  • Trimethoprim, Sulfamethoxazole Drug Combination

Substances

  • Drug Combinations
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Trimethoprim
  • Sulfamethoxazole