Microprocessor-assisted plethysmograph for the measurement of mouse paw volume

J Pharmacol Methods. 1984 Sep;12(2):149-53. doi: 10.1016/0160-5402(84)90032-9.

Abstract

A sensitive and reproducible method of measuring mouse paw volume was developed by interfacing a Mettler DeltaRange top-loading balance with a microcomputer. This methodology combined ease of operation and precision with the advantages of computer-controlled data processing and archivable storage of data.

MeSH terms

  • Animals
  • Calibration
  • Chlorpheniramine / pharmacology
  • Computers*
  • Edema / chemically induced
  • Edema / pathology
  • Edema / veterinary
  • Foot / anatomy & histology*
  • Hindlimb
  • Histamine Antagonists
  • Male
  • Mice / anatomy & histology*
  • Mice, Inbred BALB C / anatomy & histology
  • Microcomputers*
  • Plethysmography / instrumentation*

Substances

  • Histamine Antagonists
  • Chlorpheniramine