A novel opioid receptor site directed alkylating agent with irreversible narcotic antagonistic and reversible agonistic activities

J Med Chem. 1980 Mar;23(3):233-4. doi: 10.1021/jm00177a002.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alkylating Agents / chemical synthesis*
  • Alkylating Agents / pharmacology
  • Animals
  • Guinea Pigs
  • In Vitro Techniques
  • Morphinans / chemical synthesis*
  • Morphinans / pharmacology
  • Muscle Contraction / drug effects
  • Muscle, Smooth / drug effects
  • Naltrexone* / analogs & derivatives*
  • Narcotic Antagonists / chemical synthesis*
  • Narcotics / chemical synthesis*
  • Oxymorphone* / analogs & derivatives*
  • Receptors, Opioid / drug effects*

Substances

  • Alkylating Agents
  • Morphinans
  • Narcotic Antagonists
  • Narcotics
  • Receptors, Opioid
  • Naltrexone
  • beta-funaltrexamine
  • oxymorphone fumarate methyl ester
  • Oxymorphone