Improved therapy of myotonia with the lidocaine derivative tocainide

J Neurol. 1980;222(4):275-8. doi: 10.1007/BF00313157.

Abstract

The antimyotonic effect of the antiarrhythmic drug tocainide was tested in 14 patients. With 1200 to 1600 mg/d all patients reported good improvement. This was substantiated by objective tests. Only four patients noticed minor side effects.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anilides / adverse effects
  • Anilides / therapeutic use*
  • Anti-Arrhythmia Agents* / adverse effects
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myotonia / drug therapy*
  • Tocainide

Substances

  • Anilides
  • Anti-Arrhythmia Agents
  • Tocainide