The principal toxin of Delphinium brownii Rydb., and its mode of action

Experientia. 1979 Oct 15;35(10):1367-8. doi: 10.1007/BF01964013.

Abstract

Examination of D. brownii, a stock-poison of Western Canada, revealed that the principal toxin was methyllycaconitine: a potent neuromuscular blocking agent which appears to act competitively at nicotinic receptors.

MeSH terms

  • Animals
  • Biological Assay
  • Diaphragm / innervation
  • Neurotoxins* / pharmacology
  • Phrenic Nerve / drug effects
  • Phrenic Nerve / physiology
  • Plants / analysis*
  • Rats
  • Structure-Activity Relationship

Substances

  • Neurotoxins